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Human kidneys and bladder anatomical medical 3d render illustration
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Perioperative management of urothelial carcinoma

Amena Ahmad, Oskar Lepiarczyk, Alison Birtle

Urothelial carcinoma (UC) is the 11th most common cancer in the UK, with approximately 11,000 new bladder cancer diagnoses annually.1 Globally, bladder cancer accounts for approximately 635,000 new diagnoses and 228,000 deaths annually, based on the latest GLOBOCAN estimates for 2024.2 Bladder cancer constitutes the vast majority of urothelial malignancies (90–95%), with upper tract urothelial […]

touchREVIEWS in Oncology & Haematology. 2026;22(2):1–8:Online ahead of journal publication

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3 Results Found for “DIPG”

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Computer Generated Image of a Human Brain Revealing Intricate Neural Network Connections
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Imipridones in Diffuse Midline Gliomas: A Review of the Timeline from Drug Discovery to Dopamine Receptor D2 and Caseinolytic Protease P (ClpP) Target Identification and the Trials Leading to FDA Approval

Christy Soares, Laura E Donovan, Byram H Ozer

Among glial tumours of the central nervous system (CNS), one of the most devastating is the category of H3K27-altered midline gliomas because of their uniform and rapid mortality, high neurological symptom burden and predilection for paediatric, adolescent and ...

touchREVIEWS in Oncology & Haematology. 2026;22(1):29–34
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Temozolomide for Paediatric High-Grade Glioma: Time for a Rethink?

Jordan Staunton, David S Ziegler

The management of children with diffuse midline gliomas (DMG) and other paediatric high-grade gliomas (pHGG) continue to present one of the most difficult challenges facing paediatric oncologists, characterized by poor patient outcomes.1 Standard of care therapy, which includes a maximal ...

touchREVIEWS in Oncology & Haematology. 2023;19(2):4-6
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Pamela Kearns: Exciting steps forward through collaborative clinical trials in paediatric oncology

Professor Pamela Kearns (Director, Cancer Research UK Clinical Trials Unit, UK) discusses some of the most important clinical trials she is currently involved with in the field of paediatric oncology. She includes: The Glo-BNHL trial, which is the largest platform ...

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