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"A mentor once told me to always stay true to my values – advice that has guided me throughout my career" Dr Eric Lander (Director of Research at Minnesota Oncology – Minneapolis, MN, USA) shares his journey and insights into the ...
The phase III PRIMA/ENGOT-OV26/GOG-3012 trial evaluated the efficacy of niraparib as a first-line maintenance treatment for patients with advanced ovarian cancer who responded to platinum-based chemotherapy. In this final analysis, no significant difference in overall survival was observed ...
In the latest edition of touchREVIEWS in Oncology & Haematology, we are pleased to present a collection of articles that delve into the latest research and advancements in the field. From innovative therapies and genetic treatments to analyses of digital ...
Breast cancer is the leading cause of cancer death in Hispanic women in the USA. According to the American Cancer Society, as many as one in nine Hispanic women will develop invasive breast cancer during their lifetime and one in 49 ...
Acute lymphoblastic leukaemia (ALL) is a group of malignant haematological disorders characterised by accumulation of lymphoid cell precursors that replace normal bone marrow elements and inhibit the production of functional blood cells.1Â ALL occurs in both children and adults, and ...
In an exciting landscape where treatment is moving towards personalised medicine, leading multiple myeloma specialist Maria Victoria Mateos shares her updates and highlights for the year ahead. Q. What are the biggest challenges you face when treating patients with multiple ...
Smoldering myeloma is an asymptomatic clonal plasma cell disorder that is characterized by the presence of ≥3 g/dl serum M-protein and/or 10–59% bone marrow plasma cell infiltration, and is a precursor stage to multiple myeloma.1 Historically, patients with smoldering myeloma ...
Myelodysplastic syndrome (MDS) is a cytogenetic, epigenetic, and immunological heterogeneous group of myeloid disorders characterized by dysplastic hematopoeisis and propensity for acute myelogenous leukemia (AML) transformation.1,2 The Surveillance, Epidemiology, and End Results (SEER) Program estimates that risk factors for the ...
While the incidence of primary breast cancer has increased recently, most patients are diagnosed with early-stage disease and good prognosis. Around 80 % of patients with early breast cancer have estrogen receptor (ER)-positive disease and their prognosis will be improved substantially ...
Multiple myeloma (MM) is an incurable plasma cell disease that comprises 1 % of all cancers and 10 % of hematologic malignancies. It primarily affects older individuals—the median age at the moment of diagnosis is 70 years—and two-thirds of multiple myeloma patients are ...
Multiple myeloma (MM) is an incurable plasma cell disease that comprises 1 % of all cancers and 10 % of hematologic malignancies. It primarily affects older individuals—the median age at the moment of diagnosis is 70 years—and two-thirds of multiple myeloma patients are ...
Overview of Registration Trials Data in Urothelial Carcinoma In total, 450 patients were treated in two phase II trials and one phase III trial that together formed the basis for the registration of vinflunine monotherapy in urothelial carcinoma patients after failure ...
An increasing proportion of elderly people attend medical oncology consultations in which many questions about appropriate treatment will be raised by the oncologist. The balance between treatment benefits (in terms of further life expectancy of the elderly) and risks (hematologic ...
Myelodysplastic Syndromes (MDS) are a heterogeneous group of clonal hematopoietic stem cell diseases characterized by morphologic changes in the bone marrow, peripheral cytopenia(s), and susceptibility to bone marrow failure with or without progression to Acute Myeloid Leukemia (AML). Although ...
The potential role of vinflunine in sequential treatment strategies for urothelial carcinoma, in both the perioperative setting and maintenance therapy, will be highlighted below. Rationale for Perioperative Systematic Therapy in Bladder Cancer The natural history and evolution of urothelial carcinoma ...
Understanding frailty has become the focus of numerous investigations but, for the moment, there is no universally accepted definition. The concept of frailty has been developing over the past two decades. From the first article that referred to this term, ...
Europe is undergoing considerable demographic change. It is estimated that people aged over 65 years will make up 28 % of Europe’s population in 2050.1 Many neoplasms develop and are diagnosed in seniors; for example, 65 % of males with prostate cancer are aged over 65 ...
Infections remain an important cause of morbidity and mortality in cancer patients, mainly those affected by haematological malignancies and those undergoing stem cell transplant (SCT).1–3 With the improvement of cancer care in the past decades, patients live longer, and immunosuppression ...
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