Search Results
18 Results Found for “thrombotic thrombocytopenic purpura”
It is with great pleasure that we present the latest edition of touchREVIEWS in Oncology & Haematology. This edition showcases the continued advances and innovation reshaping cancer care, as well as highlighting the continued unmet needs and challenges associated with ...
The first primary microangiopathic haemolytic anaemia was identified as thrombotic thrombocytopenic purpura (TTP) by Dr Moschowitz in 1924. At that time, the classic pentad of clinical features, still used today, included fever, erythrocyte fragmentation, thrombocytopenia, kidney injury and neurologic injury.1 It ...
Dr Spero R Cataland (The Ohio State University, Wexner Medical Centre, Columbus, OH, USA) joins us for Rare Disease Day to discuss the importance of rapid diagnosis of acquired thrombotic thrombocytopenic purpura (aTTP), a rare blood disorder in which blood ...
Therapeutic plasma exchange (TPE) is an extracorporeal technique that involves separating a large volume of a patient’s plasma from the cellular components of the blood and replacing it with appropriate fluids.1 In patients with conditions that are induced and/...
Diagnosis is often delayed in patients with Gaucher disease type 1 Case 1 A 37-year-old Caucasian woman with spherocytosis reported since childhood presented with swollen ankles, gradually increasing abdominal girth, sudden weight gain (3 kg in 6 days), fatigue and exertional dyspnoea. Patient history ...
Classification The two basic forms of thrombotic microangiopathies, excluding disseminated intravascular coagulation (DIC), include thrombotic thrombocytopenic purpura (TTP), and hemolytic uremic syndrome (HUS). Early historic reports noted the presence of hemolytic anemia and thrombocytopenia in both disorders and suggested differentiation ...
Thrombotic thrombocytopenic purpura (TTP) is an acute prothrombotic disorder resulting from a deficiency of the von Willebrand factor cleavage protease ADAMTS13.1 The enzyme ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats) cleaves the peptide bond between Tyr-842 and Met-843 ...
This edition of European Oncology & Haematology is notable for the breadth of information presented. Topics range from a paper by Gianni Bisogno and colleagues on very rare tumours in paediatric patients, their experience in gathering a database and the ...
Idiopathic or immune thrombocytopenic purpura (ITP) is an autoimmune condition characterised by an abnormally low number of platelets in the circulating blood. Initially, ITP was thought to be caused by antibody-mediated platelet destruction,1 but better understanding of the pathogenesis of ...
To write a dissertation on coagulopathies in the era of biotechnology, protein mapping, and recombinant technology would require more space than allotted. Therefore, we confine ourselves to several areas: hemophilia, von Willebrand’s disease (VWD), immune thrombocytopenic purpura (ITP), and ...
When choosing the topics to cover in a reasonable and readable space in US Hematology 2007, we had to pare down the field. Experienced hematologists were chosen to help elucidate current thinking and controversies. When choosing the topics to cover in ...
Idiopathic thrombocytopenic purpura (ITP) is a primary acquired disease of adults and children characterised by transient or persistent decrease of the platelet count.1,2 Bleeding may be severe and is usually related to the platelet count. When platelet count is lower ...
In the case of an isolated chronic thrombocytopenia in an adult, the diagnostic procedure is well established. First, several causes must be ruled out. These include: • false thrombocytopenia diagnosis caused by platelet aggregation and clumping in the presence of ethylenediaminetetraacetic ...
Immune-mediated haematological disorders are a heterogeneous group of disorders characterised by immune-mediated destruction of blood cells, leading to anaemia, neutropenia or thrombocytopenia or to a combination of two or all of them. Immune-mediated anaemia can be caused directly by destruction ...
Thrombotic thrombocytopenic pupura (TTP) is a life-threatening disease characterised by microangiopathic haemolytic anaemia, consumptive thrombocytopenia and various organ dysfunctions, such as neurological symptoms, renal damage and fever.1 In order to ensure best treatment responses, early diagnosis and appropriate intervention are ...
Primary immune thrombocytopenia (ITP), until recently referred to as idiopathic thrombocytopenic purpura (ITP), is an acquired autoimmune disorder defined by isolated thrombocytopenia (platelet count 450x109/l). In phase II of the same trial, 21 patients were randomly assigned to receive six ...
Corticosteroids are typically used as initial treatment, but if platelet levels fall precipitously or the clinical situation is serious and there is a need to rapidly raise the count, intravenous immune globulins (including anti-D) may be administered. A variety of ...
Log into your Touch Account
Keep track of your clinical interests and newsletter subscriptions.
Sign up with an Email
Or use a .
Register now for FREE access
Already registered? Login below.
