Gastrointestinal Oncology

Hyun C Chung, ASCO GI 2021: Results from the LEAP-005 Study

Published Online: February 1st 2021

We were delighted to talk to Hyun C Chung (Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea) around the findings from his study of lenvatinib plus pembrolizumab in patients with previously treated selected solid tumors (Clinical Trial Identifier: NCT03797326).

The abstract ‘LEAP-005: A phase II multicohort study of lenvatinib plus pembrolizumab in patients with previously treated selected solid tumors: Results from the gastric cancer cohort.’ (ABSTRACT NUMBER: 230) was presented at the virtual ASCO Gastrointestinal Cancers Symposium 2021, 15-17 January, 2021.

Questions

  1. Could you tell us a little about the aims and design of the LEAP-005 study? (0:05)
  2. What have been the efficacy and safety findings of the study to date? (1:37)
  3. On the basis of these findings, how will the study proceed? (3:32)

Disclosures: Hyun C Chung discloses Grant/Research Support from Lilly, GSK, MSD, Merck-Serono, BMS/Ono, Taiho, Amgen, Beigene, Incyte and Zymework; Honoraria from Merck-Serono and Lilly; Consultation for Taiho, Celltrion, MSD, Lilly, BMS, Merck-Serono, Gloria, Beigene, Amgen and Zymework.

Support: Interview and filming supported by Touch Medical Media.

Filmed as a highlight of ASCO GI 2021 (Virtual).

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