12 Results Found for “paediatrics”
Physician burnout is at a critical point. In this episode, Nicky speaks with Dr Alfred Atanda about why so many physicians are burning out and what can be done to change the trend. From personal experience to system-wide solutions, Dr Atanda shares valuable insights on improving physician well-being and building a more supportive healthcare culture.
The management of children with diffuse midline gliomas (DMG) and other paediatric high-grade gliomas (pHGG) continue to present one of the most difficult challenges facing paediatric oncologists, characterized by poor patient outcomes.1Â Standard of care therapy, which includes a maximal ...
Welcoming the 2020 EMA/EC progress report on the Action Plan on Paediatrics ACCELERATE is recognised as a successful example in addressing unmet medical needs in children and adolescents In December 2020, the European Commission (EC) and European Medicines Agency (EMA) published ...
Acute lymphoblastic leukaemia (ALL) is the most common malignancy diagnosed in children and accounts for more than one-quarter of all paediatric cancers.1Â Around 85% of cases are B-cell precursor ALL (B-ALL).1Â Dramatic improvements in survival rates have been achieved in newly-diagnosed ...
The rate of childhood cancer caused by a genetic predisposition is now estimated around 8.5%.1 While proposing a genetic counselling has been classically considered as part of good clinical practice for few malignancies (retinoblastoma, adrenocortical tumours, choroid plexus carcinoma), its actual ...
Malignant tumours are relatively uncommon in children, especially considering the incidence of cancer in adults. The difficulty of performing meaningful studies due to the limited numbers of patients treated at each paediatric oncology centre has encouraged oncologists to embark on ...
The symptoms of sickle cell disease (SCD) as well as underlying disease processes affect sleep across development, which has important implications for academic and behavioural functioning and overall health outcomes in children and adolescents with SCD. High frequencies of arousals ...
The bleeding disorder immune thrombocytopenic purpura (ITP) is a model for immunological research and new biological treatment modalities of chronic inflammatory and autoimmune disorders. In ITP, immunologically susceptible subjects are recognisable by disturbances of the immune response on various levels. ...
Polycythaemia vera (PV), essential thrombocythaemia (ET) and primary myelofibrosis (PMF) are classified as Philadelphia-negative chronic myeloproliferative disorders (Ph-MPDs), clonal haematopoietic disorders1,2 that result in overproduction of mature myeloid cells and that are characterised by an increased risk of thrombotic and/...
Cancer is predominantly a disease of adults and the elderly. Fifty per cent of cancers occur after the age of 70 years, and 150,000 new cancers are diagnosed in France every year. Most adult cancers are slowgrowing adenocarcinomas. In contrast, childhood cancers (...
Radiation therapy as a means to improve outcome for a patient suffering from medulloblastoma was first used by Cushing in the 1920s. In 1953 Patterson and Farr reported their success on 27 medulloblastoma patients treated with craniospinal irradiation.1 As technology has improved, ...
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