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This issue of touchREVIEWS in Oncology & Haematology brings together a diverse collection of articles reflecting the growing complexity of cancer care and the continued evolution of precision medicine across tumour types. From rare malignancies and treatment-related challenges to emerging targeted therapies and novel biological insights, the contributions highlight both recent progress and the significant […]

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touchVisionary Voices
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Your clinical career is shaped not only by what you know, but by who helps you navigate what comes next. Join us for the final episode in our mini-series exploring non-clinical skills that can help you thrive in your clinical career. Today we explore how to develop the right team around you to support your work, and what building that bench can mean for your career, and the life you build alongside it.

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This issue of touchREVIEWS in Oncology & Haematology brings together a diverse collection of articles reflecting the growing complexity of cancer care and the continued evolution of precision medicine across tumour types. From rare malignancies and treatment-related challenges to emerging ...

3d medical illustration of lung cancer
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Christopher R Pallas, Daniel R Carrizosa, Kathryn F Mileham

Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related mortality worldwide.1 Over the past two decades, the molecular characterization of NSCLC has transformed the therapeutic landscape by enabling the development of targeted therapies that have significantly improved outcomes ...

Computer Generated Image of a Human Brain Revealing Intricate Neural Network Connections
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Among glial tumours of the central nervous system (CNS), one of the most devastating is the category of H3K27-altered midline gliomas because of their uniform and rapid mortality, high neurological symptom burden and predilection for paediatric, adolescent and ...

23 mins
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Experts highlight the remaining unmet need in RRMM and how treatment with CAR-T cell therapy may improve patient outcomes.

16 mins
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Join leading oncologists as they discuss the latest long-term data from pivotal trials with abemaciclib plus endocrine therapy, in patients with HR+, HER2-, node-positive, high-risk early breast cancer.

3 minutes
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Learn how RAS proteins play a crucial role in the regulation of cell proliferation and survival in normal cells. Oncogenic mutations in the RAS gene can drive cancer initiation and progression through disruption of this regulatory balance.

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An immunosuppressed person is one whose immune function is impaired by underlying disease and/or immunosuppressive medications, resulting in reduced immunosurveillance against malignant cells and increased vulnerability to opportunistic infections. Longstanding immunosuppression has been linked to increased risk for cutaneous (...

A Detailed 3D Depiction Of The Small Intestines Of A Human Female
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Small bowel adenocarcinoma (SBA) is a rare gastrointestinal malignancy, accounting for about 1–3% of gastrointestinal cancers.1,2 Its reported incidence has increased in recent decades, likely reflecting improved detection by balloon-assisted and capsule endoscopy and the more widespread use of cross-sectional imaging.3,4 ...

touchVisionary Voices
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We often focus on clinical excellence, but spend less time developing broader skills that could help us better lead with purpose and build more fulfilling, impactful careers. In this episode, part of a mini-series in partnership with LEADderm, Dr Jennifer Soung and Denise Mann explore how clinicians can engage with the media to educate, empower and extend their impact beyond the clinic.

Microscopic macro view of pancreatic cancer cells showing abnormal cell structure irregular nuclei aggressive growth inside glandular tissue dark medical background
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Sakhr Alshwayyat, Noor Almasri, Karam Maraqa

Pancreatic cancer (PC) is the tenth most common cancer in 2024, with 66,440 new cases and 51,570 deaths.1,2 Globally, the prevalence varies from 10/100,000 cases in the Americas and Europe to 0.9/100,000 cases in South Central Asia and most of Africa.3 Currently, it has the ...

Macro image of a needle being pricked at a cancer cell. Research of cancer diseases, viruses in infected organism , viral disease epidemic, vaccine background.
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Rafael Alvim Pereira, Milena Tumelero, Wallace Klein Schwengber

Immune checkpoint inhibitors (ICIs) act by blocking inhibitory pathways such as programmed cell death protein 1 (PD-1), programmed cell death ligand 1 (PD-L1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), thereby restoring T-cell activity and promoting tumour cell destruction.1,2 The ability of tumours ...

Career in pharma, Sian Kneller, Med comms, clinicians
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Whether you’re working in an agency, in a clinical role, or in academia, many healthcare professionals wonder what lies behind the doors of the pharmaceutical industry. In this episode, Gina is joined by Sian Kneller, Director of Global Content Design at GSK and Founder of The Agency Advantage, to unpack exactly what it takes to make the leap. With over 20 years’ experience, from medical writer to leading global medical affairs strategy, Sian now helps others make a successful move into pharma. In this episode she shares what the transition really looks like, which transferable skills matter most, and how you can stand out in a competitive field.

36 mins
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CML experts consider early-line treatment and how quality of life can be optimized.

touchVisionary Voices
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In this episode, Nicky speaks with Prof. Georgina Ellison-Hughes from King’s College London about the groundbreaking field of senolytics and their potential to advance the treatment of age-related diseases. From understanding the science behind cellular senescence to how senolytic drugs work and what early clinical trials reveal, this episode explores an exciting frontier in longevity medicine.

A visualization of human health and digestion issues, featuring a medical glow around the anatomy of the stomach and intestines
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The intestinal microbiota, composed of approximately 1,000 species and over 100 trillion micro-organisms, plays a vital role in host physiology, including metabolism, barrier function and immune regulation.1 Disruption of this delicate host–microbiota balance – known as dysbiosis – has been implicated in the ...

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It is with great pleasure that we present the latest edition of touchREVIEWS in Oncology & Haematology. This edition showcases the continued advances and innovation reshaping cancer care, as well as highlighting the continued unmet needs and challenges associated with ...

medical illustration concept symbol as a group of human blood cells
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The first primary microangiopathic haemolytic anaemia was identified as thrombotic thrombocytopenic purpura (TTP) by Dr Moschowitz in 1924. At that time, the classic pentad of clinical features, still used today, included fever, erythrocyte fragmentation, thrombocytopenia, kidney injury and neurologic injury.1 It ...

Abstract Lungs with red human bronchial tree structure.
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Kübra Canaslan, Farheen Vhora, Fatemeh Ardeshir-Larijani

Early-onset lung cancer is typically defined as occurring in individuals aged 18–50 years, although there is no universally accepted definition.1–3 This entity, though rare, poses unique diagnostic and therapeutic challenges. This article synthesizes current evidence on the unique features and management ...

67 mins
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Learn from an expert panel about individualizing 1L treatment options for patients with la/mUC.

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Expert recommendations on referral practices for CAR T-cell therapy eligibility compared with standard of care.

52 mins
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Watch in two short videos, leading thoracic oncologists share 2025 data on CheckMate 816 and CheckMate 77T.

27 mins
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For HCPs in: Brazil, Germany, and Spain

Watch focused presentations from Dr Tal Sella and Dr Alessandra Morelle, as they explore the latest clinical and real-world data on CDK4/6 inhibitors in HR+ HER2- early breast cancer (EBC).

23 mins
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Understand the efficacy of Isa-VRd on MRD status, quality of life and long-term PFS in newly-diagnosed multiple myeloma.

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  • Editorial Board

    Introducing the Editorial Board of touchREVIEWS in Oncology & Haematology, who support our mission to advance medical knowledge and practice by ensuring the integrity, relevance, and impact of the content we publish. Together, we strive to foster a vibrant academic community and contribute to the continuous improvement of healthcare worldwide.

    View All Members

    Axel Merseburger

    University Hospital Schleswig-Holstein, Lübeck, Germany

    Genitourinary Cancers

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    Axel Merseburger

    Editor-in-Chief

    Professor of Urology and Chairman of the Department of Urology at the University Hospital Schleswig-Holstein in Lübeck, Germany

    University Hospital Schleswig-Holstein, Lübeck, Germany

    Biography

    Prof. Dr. med. Axel Stuart Merseburger is a highly experienced urologist with over 21 years of practice. He works at the Department of Urology at the University Hospital Schleswig-Holstein in Lubeck, Germany and specializes in urology and robotic surgery. Dr Merseburger is considered an expert in his field with a wide range of qualifications and achievements. Having studied medicine at top institutions such as the Hannover Medical School and the Harvard Medical School, Dr Merseburger has gained extensive knowledge and expertise. He has completed various fellowships and training, including a scholarship at the Uniformed Services University in Washington and a fellowship at the Henry M Jackson Foundation Center for Prostate Disease Research. Dr Merseburger has published 442 scientific publications, demonstrating his dedication to research and innovation. He has received numerous awards and prizes, including the Werner Staehler Memorial and Urologia Internationalis prizes. With his wealth of experience and expertise, Dr Merseburger is known for his contributions to the field of urology. He is highly regarded for his skills in robotic surgery and his focus on prostate cancer. His dedication to improving patient outcomes and advancing the field of urology makes him a highly respected and trusted doctor. Overall, Prof. Dr. med. Axel Stuart Merseburger is an accomplished urologist who brings knowledge and expertise to his practice. His dedication to research, innovative treatments and patient care makes him a valuable asset to the medical community.

    Sara M Tolaney

    Section Editor

    Sara M Tolaney

    Dana-Farber Cancer Institute, Boston, MA, USA

    Breast Cancer

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    Sara M Tolaney

    Section Editor

    Chief, Division of Breast Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

    Dana-Farber Cancer Institute, Boston, MA, USA

    Biography

    Dr. Tolaney is Chief of the Division of Breast Oncology at Dana-Farber Cancer Institute, and Associate Professor of Medicine at Harvard Medical School.  She is a breast medical oncologist whose research focuses on the development of novel therapies in the treatment of breast cancer.  She has been instrumental in developing several treatment approaches for breast cancer, including approaches focused on tailoring therapy for early stage HER2+ disease, use of cdk 4/6 inhibitors, antibody drug conjugates, and immunotherapy. She is a member of the National Cancer Institute Breast Cancer Steering Committee and is Vice Chair for Late-Stage Development in Breast Cancer in the Alliance for Clinical Trials in Oncology. Her research has been funded by the Breast Cancer Research Foundation and Susan G. Komen.  She currently chairs multiple phase 3 trials in breast cancer and serves on several steering committees for practice-changing trials.  Her work has been published in journals such as the New England Journal of Medicine, Lancet, Lancet Oncology, Journal of Clinical Oncology, and others.  She received her undergraduate degree from Princeton University in 1998 and her medical degree from UC San Francisco in 2002. She subsequently completed her residency in Internal Medicine at Johns Hopkins University, and fellowships in hematology and medical oncology at Dana-Farber Cancer Institute. She obtained a Masters in Public Health from the Harvard School of Public Health in 2007.

    Axel Merseburger

    Editor-in-Chief

    Domenica Lorusso

    Section Editor

    Domenica Lorusso

    Humanitas Hospital San Pio X, Milan, Italy

    Gynaecological Cancers

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    Domenica Lorusso

    Section Editor

    Director, Gynaecological Oncology Unit, Humanitas Hospital San Pio X, Milan, and Full Professor of Obstetrics and Gynaecology, Humanitas University, Rozzano, Milan

    Humanitas Hospital San Pio X, Milan, Italy

    Biography

    Domenica Lorusso, MD, PhD, is Director of Gynaecological Oncology Unit at Humanitas Hospital San Pio X, Milan, and Full Professor of Obstetrics and Gynaecology, Humanitas University, Rozzano, Milan. Prof. Lorusso has been involved in gynecological oncology research for more than 25 years and has conducted or participated in approximately 250 phase I-IV clinical trials in gynecological malignancies. At present she is Principal Investigators of more than 60 studies.

    Prof. Lorusso is responsible for the Clinical Trials Committee of the MITO (Multicenter Italian Trials in Ovarian Cancer and Gynaecological Malignancies) Group, which includes more than 150 Italian centers involved in gynecological oncology research. She is a member of the Board of Directors of Gynaecological Cancer Intergroup including 23 international research groups involved in the promotion and conduction of high-quality clinical trials to improve outcomes for women with gynecological cancers. Prof. Lorusso is also an active member of ENGOT (European Network of Gynaecological Oncological Trial groups), an international organization which coordinates and promotes clinical trials within Europe for patients with gynecological cancers where she chairs the Gynecological Cancer Academy. She is a member of the Board of Director of the European Society of Gynecological Oncology (ESGO). She has also co-authored about 300 international oncology publications. She is author of national and international guidelines on treatment of ovarian, cervical and endometrial cancer.

    Prof. Lorusso’s key goals are to ensure best treatment to all patients and promote the clinical research, international trial collaborations and educations.

    Sara M Tolaney

    Section Editor

    Matti S Aapro

    Section Editor

    Matti S Aapro

    Multidisciplinary Oncology Institute, Genolier, Switzerland

    Supportive Cancer Care

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    Matti S Aapro

    Section Editor

    Dean, Multidisciplinary Oncology Institute, Genolier, Switzerland

    Multidisciplinary Oncology Institute, Genolier, Switzerland

    Biography

    Dr Aapro coordinates the Sharing Progress in Cancer Care (SPCC) program of the European School of Oncology (ESO) and serves the International Society for Geriatric Oncology (SIOG) as an Executive Board member. He has been a member of the board of the European Organization for Research and Treatment of Cancer (EORTC) and of the European Society of Medical Oncology (ESMO). He is Past President of the Multinational Association for Supportive Care in Cancer (MASCC), and is now on its Board of Directors for 2012 to 2014.

    Dr Aapro is Editor-in-Chief of Critical Reviews in Oncology/Hematology, Associate Editor for the geriatric section of the Oncologist, and is Founding Editor of the Journal of Geriatric Oncology, and was Associate Editor for Annals of Oncology. He has authored more than 250 publications and his major interests are new drug development, breast cancer, supportive care, and cancer in the elderly.

    Dr Aapro received the 2012 ASCO BJ Kennedy prize.

    Domenica Lorusso

    Section Editor

    Axel Merseburger

    Editor-in-Chief
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