An Introduction to Paediatric Oncology
Paediatric cancers are treated by a multidisciplinary team that includes paediatric oncologists, radiation oncologists, paediatric surgeons and specialist nurses. Significant treatment advances have been made over the past decade, including the introduction of targeted therapies such as TKIs and immunotherapies, which have dramatically improved patient outcomes across numerous cancer types.
Expert video highlights and insights from the conference hub and comprehensive peer-reviewed articles from our journal portfolio provide updates on the ever-changing landscape.
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Paediatric Oncology Content
Guillaume Canaud, ESMO 2021: EPIK-P1 Study of Alpelisib in the Treatment Patients With PIK3CA-related Overgrowth Spectrum
touchONCOLOGY joins Professor Guillaume Canaud (Necker–Enfants Malades Hospital, Paris, France), to discuss EPIK-P1, a retrospective chart review study of patients with PIK3CA-related overgrowth spectrum who have received alpelisib as part of a compassionate use programme. Questions 1. Could you tell us a little about PIK3CA-related Overgrowth Spectrum (PROS), the clinical manifestations and prognosis? (00:25-01:11) 2. […]
Childhood Cancer Awareness Month: Shine Gold on Our Young Heroes & Survivors!
Honouring the children and adolescents battling cancer September is Childhood Cancer Awareness Month: A time to recognise the children and adolescents affected by cancer at global and European scale. One would expect that it should be “children first” but sadly too often it is “children last”. There are serious inequalities in access to the best […]
Letter from the President of the European Society for Paediatric Oncology (SIOPE) – COVID-19: Resources and Guidance
Dear friends and colleagues in the SIOP Europe Community, We are all currently facing difficult challenges and stresses, both personal and professional, in the unprecedented circumstances of the COVID-19 pandemic. As we are now several weeks into the pandemic reaching Europe, the impact has been felt in all European countries and there is naturally anxiety […]
Teenagers with cancer set to benefit from international initiative aimed at lowering the age of participation to potentially life-saving treatments
According to the multi-stakeholder international FAIR (Fostering Age Inclusive Research) Trials Initiative, teenagers with cancer must no longer be blocked from entering adult clinical trials. Teenagers with cancer must no longer be blocked from entering adult clinical trials, according to the multi- stakeholder international FAIR (Fostering Age Inclusive Research) Trials Initiative. The FAIR Trials […]
2019 Highlights – A look back at SIOP Europe’s year
During 2019, SIOP Europe achieved many exciting milestones, as we launched several new activities. I am delighted to share the highlights of this ‘action packed’ year. 1st SIOP Europe Annual Meeting successfully launched in Prague The first edition of the SIOP Europe Annual Meeting was successfully launched in Prague on 20–24 May. Not only did […]
Fighting inequalities in childhood cancer
Childhood cancer care continues to suffer from widespread inequalities, says Pamela Kearns. Inequalities in access to the best available care, expertise and knowledge for children and young people with cancer remains a critical issue across Europe. These inequalities contribute to 20 percent differences in survival rates when comparing North and Western Europe with Central and […]
Cornelis van Tilburg, ASCO 2019 – Larotrectinib in paediatric TRK fusion cancer
At the ASCO 2019 annual meeting, Cornelis van Tilburg discusses findings from recent studies investigating the efficacy and safety of larotrectinib in paediatric TRK fusion cancer patients (NCT02637687 and NCT02576431) and what this means for the future. Questions 1.What percentage of paediatric tumours have tropomyosin receptor kinase (TRK) fusions and in what tumour types are […]
Late Complications of Cancer in Childhood and Adolescence
Oncology & Hematology Review, 2013;9(1):52–9 DOI: https://doi.org/10.17925/OHR.2013.09.1.52
Since the 1960s, overall survival for all childhood cancers has substantially increased such that currently nearly 80 % of children will survive to five years following diagnosis, compared with 30 % 50 years ago. For most childhood cancers, survival at five years from therapy does not decrease significantly, and the vast majority of these children […]
Bronchial Carcinoid Tumours in Children – A Review
European Oncology & Haematology, 2011;7(3):196-9 DOI: https://doi.org/10.17925/EOH.2011.07.03.196
Carcinoid tumours are rare, malignant neuroendocrine neoplasms first described in 1888 in the ileum1 and called ‘Karzinoide’ by Oberndorfer in 1907.2 Neuroendocrine cells were originally called clear cells and later amine precursor uptake and decarboxylation (APUD) system cells.3 The term neuroendocrine was introduced with the finding that these cells are capable of producing bioactive amines […]
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