Despite advances in radiotherapy, chemotherapy, and targeted therapy for gastrointestinal cancers, the disease has high recurrence rates and a poor prognosis. However, increased understanding of molecular biology has enabled significant progress in the management of oesophageal, gastric, liver, colorectal and pancreatic malignancies. Immunotherapies such as PD1 inhibitors plus HER-targeted therapies have improved survival in several gastrointestinal tumour types, while PARP inhibitors have been introduced as first-line maintenance treatment for BRCA-mutated metastatic pancreatic cancer.
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In this episode, we explore the future of continuing medical education (CME) with the team behind touchIME. Hannah Fisher and Matthew Goodwin share insights into global and US trends, the importance of patient inclusivity and how educational outcomes are evolving to better measure the direct impact of learning on clinical practice and patient care.
We are delighted to present the latest edition of touchREVIEWS in Oncology & Haematology. This issue underscores the evolving landscape of cancer therapeutics, showcasing advances across a wide range of malignancies, from haematologic diseases to solid tumours, through novel mechanisms, ...
At a time when cancer research is experiencing uncertainty and setbacks in America, the Colorectal Cancer Alliance (Alliance) is strengthening its commitment to its Project Cure CRC initiative because tomorrow can’t wait. Project Cure CRC funds cutting-edge colorectal cancer (CRC) research and aims to improve patient outcomes through its dynamic patient navigation portal, BlueHQ.org.
Dr Satish Nadig describes Northwestern Medicine’s first use of the RAPID procedure to treat metastatic colorectal cancer with liver transplantation. He outlines the innovative surgical techniques, the promise of the CLEAR program, and the future potential of machine perfusion technology to extend transplant opportunities to more patients.
Rare gastrointestinal (GI) cancers present unique challenges in diagnosis, treatment and research. Dr. Benjamin Weinberg discusses three of the rarest GI cancers: small bowel, appendix and anal cancer.
[embed]https://www.youtube.com/watch?v=Cd77dEeZfrc[/embed] As the leading nonprofit organization dedicated to ending the disease, the Colorectal Cancer Alliance (Alliance) continues to break boundaries in colorectal cancer care. Its Project Cure CRC research initiative ...
Despite being considered a rare type of malignancy, constituting only 3% of all gastrointestinal cancers, the incidence of biliary tract cancers (BTCs) has been increasing worldwide in recent years, with about 20,000 new cases annually only in the USA.1–3 These cancers arise ...
“By engaging in research early, young oncologists can contribute to scientific discovery” Q1. What inspired you to pursue a career in oncology? Initially, as a gastroenterologist, I experienced many benign diseases and endoscopic procedures, but oncology was what interested me ...
What’s new in GI oncology? With the 2025 ASCO Gastrointestinal Cancers Symposium still fresh in our minds, we hear from leading experts on the key abstracts and presentations from the conference in the fields of colorectal and pancreatic cancer. Circulating ...
Experts discuss the role of RAS mutations in solid tumours and how they may be targeted to improve outcomes.
It is with great pleasure that we present the latest edition of touchREVIEWS in Oncology & Haematology. This issue highlights the remarkable progress and innovation shaping the fields of oncology and haematology, featuring articles that delve into both emerging therapies ...
Oesophageal cancer is the eighth most commonly diagnosed cancer and is the sixth leading cause of cancer death worldwide.1,2 Worldwide, around 604,100 new instances of oesophageal cancer were recorded in 2020, leading to approximately 544,100 deaths. This translates to a standardized incidence rate ...
Rat sarcoma virus (RAS) proteins are a family of prototypical oncogenes frequently mutated in human cancers. Mutations in the RAS gene account for 19% of all pathogenic alterations and are the subject of extensive research in molecular and clinical oncology.1 The ...
In this interview, Dr Michael K. Gibson (Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA), an expert in head and neck and gastrointestinal (GI) oncology shares his personal journey, reflecting on how early experiences with cancer shaped his ...
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