An Introduction to Gynaecological Cancers
The treatment landscape for gynaecological cancers, especially ovarian cancer, has evolved over recent years. Late diagnosis means ovarian cancer is often detected at an advanced stage, but the introduction of targeted therapies and immunotherapies have widened the treatment landscape. Cervical cancer has a high survival rate if detected early, and therefore screening continues to be an important issue.
Expert video highlights, insights from the conference hub and comprehensive peer-reviewed articles from our journal portfolio provide updates on the changing treatment landscape. To learn more about how the latest developments impact on patient outcomes, view our expert-led learning activities.”
Gynaecological Cancers Content
PARP inhibitors as first-line maintenance therapy in ovarian cancer: How can data from ESGO 2022 guide clinical practice?
Watch this two-part activity exploring the latest data on the use of PARP inhibitors in first-line maintenance therapy in ovarian cancer. Filmed following the ESGO European Congress on Gynaecological Oncology 2022. Part 1: Watch gynaecological cancer expert Prof. Jonathan Ledermann review key data from ESGO 2022 Watch Now Part 2: Watch leading experts consider what these data may mean for global and regional practice Select An Interview
- Outline the latest clinical trial data for PARP inhibitors in the first-line maintenance setting for advanced ovarian cancer
- Describe real-world data on the use of PARP inhibitors in the first-line maintenance setting for advanced ovarian cancer
- Discuss how the clinical trial and real-world data may impact the use of PARP inhibitors in clinical practice
Paul DiSilvestro, ESMO 2022: SOLO1/GOG-3004 trial – Olaparib for the treatment of advanced ovarian cancer – Overall survival findings at 7 years
The Phase III SOLO1/GOG-3004 trial (NCT01844986), investigated maintenance olaparib, which provided sustained benefit beyond the end of treatment in patients with newly diagnosed advanced ovarian cancer and a BRCA mutation. Prof. Paul DiSilvestro (Brown University, Providence, RI, USA) joins touchONCOLOGY to discuss the efficacy and safety of maintenance olaparib, and overall survival findings at 7 years. […]
Keiichi Fujiwara, ESMO 2022: Phase 3 GOTIC-002 LUFT study results – Chemotherapy with tegafur-uracil for locally advanced cervical cancer
Maintenance chemotherapy with oral tegafur-uracil (UFT) after surgery has been shown to prolong survival in lung, breast, gastric and colon cancer. Dr Keiichi Fujiwara (Saitama Medical University International Medical Centre, Saitama, Japan) joins touchONCOLOGY to discuss the phase 3 GOTIC-002 LUFT study results, investigating the efficacy of maintenance chemotherapy using UFT following concurrent chemoradiotherapy for […]
Keiichi Fujiwara, ESMO 2022: Clinical trial highlights in gynaecological cancer
Dr Keiichi Fujiwara joins touchONCOLOGY to discuss his thoughts on the latest clinical trial highlights at European Society for Medical Oncology (ESMO) 2022 in gynaecological cancers, specifically the GOTIC-002 LUFT study. Watch Dr Keiichi Fujiwara’s interview at ESMO 2022, on the Phase 3 GOTIC-002 LUFT study results – chemotherapy with tegafur-uracil for locally advanced cervical […]
Clinical decision making in advanced ovarian and advanced/recurrent endometrial cancers
Promotional content from GSK. Watch leading experts Jalid Sehouli, Nicole Concin, Shibani Nicum and Lynn Buckley discuss how to individualise clinical decision making for gynaecological cancers.
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Maximizing the potential of PARP inhibitors as first-line maintenance therapy in ovarian cancer: Improving patient identification and treatment selection
Watch ovarian cancer experts discuss key considerations for optimizing patient outcomes with PARP inhibitors as first-line maintenance therapy.
- Discuss the rationale for using PARP inhibitors in the first-line maintenance treatment of advanced ovarian cancer
- Identify patients who may benefit from a PARP inhibitor in the first-line maintenance setting
- Describe the key factors that can inform selection of the most appropriate PARP inhibitor for each patient
Domenica Lorusso, ASCO 2022: Trabectedin for the treatment of recurrent ovarian, primary peritoneal, or fallopian tube cancers – Phase 3 MITO23 trial results
The phase 3 MITO23 trial investigated trabectedin (ET-743) single agent versus clinician’s choice chemotherapy in recurrent ovarian, primary peritoneal, or fallopian tube cancers of BRCA-mutated or BRCAness phenotype patients Dr Domenica Lorusso (Fondazione IRCCS National Cancer institute of Milan, Milan, Italy) discusses the rationale for the trial, trabectedin’s mode of action, the phase 3 results, […]
Pembrolizumab and Chemotherapy in Cervical Cancer: A New Standard of Care?
touchREVIEWS in Oncology & Haematology. 2022;18(1):2–8 DOI: https://doi.org/10.17925/OHR.2022.18.1.2
Cervical cancer (CC) remains one of the most frequent cancers in women, representing the fourth cause of neoplasia in women in terms of incidence, and has a high lethality rate.1 Indeed, worldwide 341,831 women die each year because of this disease, with a mortality rate that varies across different countries, with, for example, less than two […]
Ruth Perets, AACR 2022: Vibostolimab/Pembrolizumab Coformulation for the Treatment of Ovarian Cancer Naive to PD-1/PD-L1 Inhibitors
We were delighted to speak with Dr. Ruth Perets (Rambam Health Care Campus, Haifa, Israel) about the efficacy and safety findings of the phase 1 study comparing vibostolimab (vibo) plus pembrolizumab (pembro) given sequentially to the coformulation of vibo/pembro in ovarian cancer naive to PD-1/PD-L1 inhibitors. The abstract ‘Safety and efficacy of vibostolimab (vibo) plus […]
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