Home > Prithviraj Bose MD, EHA 2019 – Sotatercept in Subjects with MPN-associated Myelofibrosis and Anaemia
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Prithviraj Bose MD, EHA 2019 – Sotatercept in Subjects with MPN-associated Myelofibrosis and Anaemia

Published Online: June 27th 2019

Professor Prithviraj Bose joins us at the EHA annual meeting in Amsterdam to discuss his presentation on sotatercept (ACE-011) in subjects with MPN-associated myelofibrosis and anaemia.

Questions
1. What are the limitations of ruxolitinib treatment for MPN-associated myelofibrosis? (0:05)
2. What is the mechanism of action of sotatercept? (0:55)
3. What is the rationale for combining sotatercept with ruxolitinib? (1:36)
4. Could you tell us a little about your recent phase II study of sotatercept and its findings? (2:27)
5. Which other emerging therapies for MPN-associated myelofibrosis seem promising? (3:48)

Filmed at the European Hematology Association (EHA) 24th congress 2019, Amsterdam, Netherlands.

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