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Amena Ahmad, Oskar Lepiarczyk, Alison Birtle

Urothelial carcinoma (UC) is the 11th most common cancer in the UK, with approximately 11,000 new bladder cancer diagnoses annually.1 Globally, bladder cancer accounts for approximately 635,000 new diagnoses and 228,000 deaths annually, based on the latest GLOBOCAN estimates for 2024.2 Bladder cancer constitutes the vast majority of urothelial malignancies (90–95%), with upper tract urothelial […]

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5 Results Found for “Merkel cell carcinoma”

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An immunosuppressed person is one whose immune function is impaired by underlying disease and/or immunosuppressive medications, resulting in reduced immunosurveillance against malignant cells and increased vulnerability to opportunistic infections. Longstanding immunosuppression has been linked to increased risk for cutaneous (...

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Welcome to the latest issue of touchREVIEWS in Oncology & Haematology. We are honoured to present a series of compelling articles that reflect cutting-edge developments and diverse perspectives in this ever-evolving field. This issue includes a series of editorials and ...

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Ruben J Cruz-Chamorro, Alberic Gan, John M Bryant

Merkel cell carcinoma (MCC) is a rare, poorly differentiated and highly aggressive neuroendocrine cutaneous cancer with a high propensity to grow rapidly and metastasize early. Merkel cell polyomavirus (MCPyV) is now estimated to be the causative factor in up to 80% ...

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Inderjit Mehmi, Kristopher P Wentzel, Omid Hamid

The antitumor activity of immune checkpoint inhibotors in various solid and haematologic malignancies has substantially increased immunotherapy implications for cancer. Once only a niche treatment for selected cancers (renal cancer and melanoma), now cancer immunotherapy has become an important option ...

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Radiotherapy, however, has many advantages in this setting, including the preservation of anatomy and avoidance of surgery, which is particularly useful in elderly patients who may be unsuitable for general anaesthetic or those on anticoagulants. The spectrum of cancers treated ...

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