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Navigating the clinical impact of TROP2-targeting in NSCLC
Learning Objectives
After watching this activity, participants should be better able to:
- Assess the efficacy and safety profiles of TROP2 ADCs compared with standard treatments in NSCLC
- Evaluate the utility of measuring TROP2 expression levels in NSCLC and the specific patient populations included in clinical trials to determine eligibility for TROP2-targeted therapies
- Develop evidence-based management approaches for specific TROP2-targeted ADC toxicities in NSCLC
Overview
In this symposium, Prof. Marina Garassino, Prof. Jarushka Naidoo and Prof. David Planchard share their insights on TROP2-targeted ADCs in NSCLC. They discuss the latest clinical trial data; challenges in using TROP2 as a biomarker in practice; and the unique side-effect profiles of ADCs, offering practical strategies for toxicity management. read more
This activity is jointly provided by USF Health and touchIME.
touchIME is an EBAC® accredited provider.
Target Audience
Oncologists, including lung cancer specialists, pulmonologists, pathologists and oncology nurse specialists
USF Accreditation
Disclosures
USF Health adheres to the Standards for Integrity and Independence in Accredited Continuing Education. All individuals in a position to influence content have disclosed to USF Health any financial relationship with an ineligible organization. USF Health has reviewed and mitigated all relevant financial relationships related to the content of the activity. The relevant relationships are listed below. All individuals not listed have no relevant financial relationships.
Faculty
Prof. Marina Garassino discloses: Speaker’s bureau and advisory panel fees from AbbVie, AstraZeneca, Bayer, Bristol Myers Squibb, Daiichi Sankyo, Eli Lilly, Gilead Sciences, IO Biotech, Janssen Pharmaceuticals, Merck & Co, Mirati Therapeutics, Natera, Novocure, Nuvation, Pfizer, Regeneron, Revolution Medicines, Roche and Takeda. Grant/research support from AIFA, AIRC, Horizon 2020, Italian MoH and TRANSCAN.
Prof. Jarushka Naidoo discloses: Advisory board or panel fees from AbbVie, Amgen, Arcus Biosciences, AstraZeneca, Bayer, Bristol Myers Squibb, Daiichi Sankyo, Elevation Oncology, Mirati Therapeutics, Novartis, Oxford Therapeutics, Pfizer, Regeneron, Roche/Genentech, Summit Therapeutics, Takeda and Zymeworks. Grant/research support from Amgen, Arcus Biosciences, Bristol Myers Squibb, Daiichi Sankyo, Mirati Therapeutics, Novartis and Roche/Genentech.
Prof. David Planchard discloses: Advisory board or panel fees from AbbVie, ArriVent BioPharma, AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Celgene, Daiichi Sankyo, Eli Lilly, GSK, Janssen Pharmaceuticals, Merck, Mirati Therapeutics, Novartis, Pfizer, Pierre Fabre, Roche, Seagen and Takeda. Clinical trials research as principal or co-investigator (institutional financial interests) fees from AbbVie, ArriVent BioPharma, AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Daiichi Sankyo, Eli Lilly, Janssen Pharmaceuticals, MedImmune, Merck, Mirati Therapeutics, Novartis, Novocure, Pfizer, Pierre Fabre, Roche, Sanofi-Aventis, Seagen, Taiho Pharma and Takeda.
Content Reviewer
Danielle Walker, DNP, APRN, AGNP-C, has no financial interests/relationships or affiliations in relation to this activity.
Touch Medical Contributors
Kathy Day has no financial interests/relationships or affiliations in relation to this activity.
USF Health Office of Continuing Professional Development and touchIME staff have no financial interests/relationships or affiliations in relation to this activity.
Requirements for Successful Completion
In order to receive credit for this activity, participants must review the content and complete the post-test and evaluation form. Statements of credit are awarded upon successful completion of the post-test and evaluation form.
If you have questions regarding credit please contact cpdsupport@usf.edu
Accreditations
Physicians
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through a joint providership of USF Health and touchIME. USF Health is accredited by the ACCME to provide continuing medical education for physicians.
USF Health designates this enduring material for a maximum of 1.25 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Advanced Practice Providers
Physician Assistants may claim a maximum of 1.25 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 CreditsTM from organizations accredited by ACCME or a recognized state medical society.
The AANPCP accepts certificates of participation for educational activities approved for AMA PRA Category 1 CreditTM by ACCME-accredited providers. APRNs who participate will receive a certificate of completion commensurate with the extent of their participation.
Date of original release: 31 March 2025. Date credits expire: 31 March 2026.
If you have any questions regarding credit, please contact cpdsupport@usf.edu
Nurses
USF Health is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.
A maximum of 1.25 contact hour(s) may be earned by learners who successfully complete this continuing professional development activity. USF Health, the accredited provider, acknowledges touchIME as the joint provider in the planning and execution of this CNE activity.
This activity is awarded 1.25 ANCC pharmacotherapeutic contact hours.
Date of original release: 31 March 2025. Date credits expire: 31 March 2026.
If you have any questions regarding credit please contact cpdsupport@usf.edu
EBAC® Accreditation
touchIME is an EBAC® accredited provider since 2023.
This programme is accredited by the European Board for Accreditation of Continuing Education for Health Professionals (EBAC®) for 70 minutes of effective education time.
The Accreditation Council for Continuing Medical Education (ACCME®), and the Royal College of Physicians and Surgeons of Canada hold an agreement on mutual recognition on substantive equivalency of accreditation systems with EBAC®.
Through an agreement between the European Board for Accreditation of Continuing Education for Health Professionals and the American Medical Association (AMA), physicians may convert EBAC® CE credits to AMA PRA Category 1 CreditsTM. Information on the process to convert EBAC® credit to AMA credit can be found on the AMA website. Other healthcare professionals may obtain from the AMA a certificate of having participated in an activity eligible for conversion of credit to AMA PRA Category 1 CreditTM.
Faculty Disclosure Statement / Conflict of Interest Policy
In compliance with EBAC® guidelines, all speakers/chairpersons participating in this programme have disclosed or indicated potential conflicts of interest which might cause a bias in the presentations. The Organizing Committee/Course Director is responsible for ensuring that all potential conflicts of interest relevant to the event have been mitigated and declared to the audience prior to the CME activities.
Faculty
Prof. Marina Garassino discloses: Speaker’s bureau and advisory panel fees from AbbVie, AstraZeneca, Bayer, Bristol Myers Squibb, Daiichi Sankyo, Eli Lilly, Gilead Sciences, IO Biotech, Janssen Pharmaceuticals, Merck & Co, Mirati Therapeutics, Natera, Novocure, Nuvation, Pfizer, Regeneron, Revolution Medicines, Roche and Takeda. Grant/research support from AIFA, AIRC, Horizon 2020, Italian MoH and TRANSCAN.
Prof. Jarushka Naidoo discloses: Advisory board or panel fees from AbbVie, Amgen, Arcus Biosciences, AstraZeneca, Bayer, Bristol Myers Squibb, Daiichi Sankyo, Elevation Oncology, Mirati Therapeutics, Novartis, Oxford Therapeutics, Pfizer, Regeneron, Roche/Genentech, Summit Therapeutics, Takeda and Zymeworks. Grant/research support from Amgen, Arcus Biosciences, Bristol Myers Squibb, Daiichi Sankyo, Mirati Therapeutics, Novartis and Roche/Genentech.
Prof. David Planchard discloses: Advisory board or panel fees from AbbVie, ArriVent BioPharma, AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Celgene, Daiichi Sankyo, Eli Lilly, GSK, Janssen Pharmaceuticals, Merck, Mirati Therapeutics, Novartis, Pfizer, Pierre Fabre, Roche, Seagen and Takeda. Clinical trials research as principal or co-investigator (institutional financial interests) fees from AbbVie, ArriVent BioPharma, AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Daiichi Sankyo, Eli Lilly, Janssen Pharmaceuticals, MedImmune, Merck, Mirati Therapeutics, Novartis, Novocure, Pfizer, Pierre Fabre, Roche, Sanofi-Aventis, Seagen, Taiho Pharma and Takeda.
Requirements for Successful Completion
Certificates of Completion may be awarded upon successful completion of the post-test and evaluation form. If you have completed one hour or more of effective education through EBAC® accredited CE activities, please contact us at accreditation@touchime.org to receive your EBAC® CE credit certificate. EBAC® grants 1 CE credit for every hour of education completed.
Date of original release: 31 March 2025. Date credits expire: 31 March 2027.
Time to Complete: 70 minutes
If you have any questions regarding the EBAC® credits, please contact accreditation@touchime.org
- Downloads including slides are available for this activity in the Toolkit
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