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Alexander Perl, EHA 2019 – The Phase III ADMIRAL Trial

Published Online: June 27th 2019

We are joined by Alexander Perl at EHA 2019 to discuss his presentation on gilteritinib significantly prolongs overall survival in patients with FLT3-mutated (FLT3MUT+) relapsed/refractory (R/R) acute myeloid leukemia (AML): results from the phase III ADMIRAL trial.

Questions
1. What are the major types of FLT3 mutation and what is their impact on prognosis? (0:05)
2. What are the major challenges in the treatment of FLT3-mutated acute myeloid leukemia (AML)? (1:05)
3. What are the advantages of gilteritinib compared to existing FLT3 inhibitors? (2:14)
4. Could you tell us a little about the ADMIRAL trial and its findings? (3:30)
5. What is the potential for using gilteritinib in the first-line treatment setting? (6:33)

Filmed at the European Hematology Association (EHA) 24th congress 2019, Amsterdam, Netherlands.

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