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Gabriela Franco Katz, Beatriz Mendes Awni Cidale, Ana Zélia Leal Pereira

This article examines current evidence supporting the use of neoadjuvant immunotherapy in patients with resectable macroscopic stage III melanoma and critically discusses the selection of appropriate adjuvant therapy following surgery. It is written in the context of emerging evidence from recent neoadjuvant trials, both in melanoma and across multiple tumor types, suggesting that pathologic response […]

Michael Atkins: Safe and Effective Use of Immune Checkpoint Inhibitors in Patients with Cancer

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Published Online: Feb 21st 2022

Dr Michael Atkins (MedStar Georgetown University Hospital, Washington, DC, USA) shares three areas for development to help improve the safe and effective use of immune checkpoint inhibitors.

1. Having a rational approach to stopping therapy (00:50-02:20)
2. An improved understanding of toxicity and response (02:20-04:25)
3. The role of combining and sequencing immunotherapy with standard treatment (04:30-06:05)

Speaker Disclosure: Michael Atkins is a member of the advisory board at: BMS, Merck, Novartis, Eisai, Aveo, Pfizer, Werewolf, Fathom, Pneuma, Leads, Pyxis Oncology, PACT, Elpis, X4Pharma, ValoHealth, ScholarRock, Surface, Takeda, Simcha, Roche and SAB Bio. He has been a consultant for: BMS, Merck, Novartis, Pfizer, Roche, Exelixis, Iovance, COTA, Idera, Agenus, Apexigen, Asher Bio, Neoleukin, AstraZeneca, Calithera, SeaGen and Sanofi. He has received research support to his institution from BMS, Merck, Pfizer, and has stock options at Werewolf, Pyxis Oncology and Elpis.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Sophie Nickelson.

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