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Endocrine therapy (ET) has changed the natural history of hormone receptor-positive (HR+) breast cancer (BC) and is the cornerstone of the treatment of HR+ BC. There are several ETs approved for the treatment of BC, including selective oestrogen receptor modulators (SERMs; tamoxifen), aromatase inhibitors (AIs; anastrazole, letrozole and exemestane) and selective oestrogen receptor degraders (SERDs; fulvestrant […]

Niels Reinmuth, ELCC 2022: Characteristics of Long-term Survivors in the CASPIAN Study

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Published Online: May 5th 2022

The CASPIAN study evaluated the efficacy and safety of durvalumab plus tremelimumab and platinum-etoposide extensive-stage SCLC. touchONCOLOGY spoke to Niels Reinmuth (Munich, Germany) to discuss the characteristics of long-term survivors in the CASPIAN study.

Clinical Trial Identification: NCT03043872

Questions

  1.       What did the CASPIAN study teach us about the efficacy and safety of durvalumab plus tremelimumab and platinum-etoposide extensive-stage SCLC? 00:18-01:58
  2.       What was the rationale for your current analysis of CASPIAN data? 01:58-02:42
  3.       What were the findings of this study and what are their clinical implications? 02:42-03:03
  4.       What questions remain unanswered and what future studies are planned? 03:03-04:04

Speaker Disclosure: Niels Reinmuth is a Speaker’s Bureau participant with: Amgen, AstraZeneca, Bristol-Myers Squibb, Boehringer Ingelheim, Daiichi Sankyo, Hoffmann-La Roche, MSD, Merck, Pfizer, and Takeda.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Sophie Nickelson.

Filmed in coverage of the European Lung Cancer Congress 2022

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