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Rat sarcoma virus (RAS) proteins are a family of prototypical oncogenes frequently mutated in human cancers. Mutations in the RAS gene account for 19% of all pathogenic alterations and are the subject of extensive research in molecular and clinical oncology.1 The RAS family consists of three major isoforms, namely the Harvey rat sarcoma virus (HRAS), the neuroblastoma RAS […]

Marcus S Noel, ASCO GI22: Latest Advances in Pancreatic Cancer Treatment

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Published Online: Mar 8th 2022

touchONCOLOGY were thrilled to speak to Professor Marcus S Noel (Medstar Georgetown University Hospital, Washington, DC, USA) to summarise the latest developments and data from the ASCO Gastrointestinal Cancers Symposium 2022.

Questions

  1.       What is the rationale for the use of L-asparaginase in the treatment of pancreatic cancer? 00:22-01:00
  2.       Could you give us an overview of the TRYbeCA 1 study? 01:00-02:31
  3.       What were the findings of the KRYSTAL-1 study in FRAS-mutated pancreatic ductal adenocarcinoma? 02:31-03:37
  4.       Following the CISPD3 trial, what is your opinion on the future of PD-1 blockade with chemotherapy in the treatment of pancreatic cancer? 03:47-04:32

Speaker Disclosure: Marcus S Noel has no conflicts of interest to declare in relation to this video.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Sophie Nickelson.

Filmed in coverage of the ASCO Gastrointestinal Cancers Symposium 2022.

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