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Selecting the optimal treatment for patients with chronic myeloid leukaemia after two prior lines of therapy

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    Faculty & Disclosures
    Prof. Simona Soverini

    University of Bologna, Bologna, Italy

    Prof. Simona Soverini is an associate professor of hematology at the Department of Experimental, Diagnostic and Speciality Medicine of the University of Bologna, and head of the Myeloid Leukemia Research group at the Institute of Hematology “Lorenzo e Ariosto Seragnoli” at the S. Orsola University Hospital in Bologna, Italy. read more

    She obtained her MSc in molecular biology and her PhD in clinical and experimental haematology from the University of Bologna. Her research focuses on chronic myeloid leukaemia and systemic mastocytosis. Prof. Soverini is author of over 170 publications in peer-reviewed journals, with a h-index of 50. She is a reviewer for a number of international journals, including Blood, Leukaemia, Haematologica, Clinical Cancer Research and the British Journal of Haematology, and sits in the editorial boards of the Journal of Hematology & Oncology, Frontiers in Oncology and the International Journal of Molecular Sciences. She is a member of the board of directors of the Italian Society of Experimental Hematology (SIES) and a member of the European Hematology Association (EHA), the American Society of Hematology (ASH) and the Society of Hematological Oncology (SOHO). She has served on the scientific program committees for EHA and SOHO congresses.

    Prof. Simona Soverini discloses: Advisory board fees from Cepheid and Blueprint Medicines. Consultancy fees from Incyte Biosciences.
    Dr Daniela Žáčková

    University Hospital Brno and Masaryk University, Brno, Czech Republic

    Daniela Žáčková, MD, PhD is consultant in haematology and associate professor at the Department of Internal Medicine Hematology and Oncology, University Hospital Brno, and Masaryk University, Brno, Czech Republic. read more

    Her scientific interest is mainly focused on the clinical and biological aspects of chronic myeloid leukemia (CML). She acts as a principal investigator of the nationwide, investigator-initiated, TKI-discontinuation, phase II trial HALF; co-investigator and national coordinator of international projects and trials, such as TIGER (CMLV) study, EURO-SKI/AFTER-SKI, PONDEROSA, and Blast Crisis Registry; and expert guarantor and national coordinator of the Czech Registry of CML patients, called INFINITY. She is a member of the European Hematology Association (EHA), European LeukemiaNet (ELN) Working Package 4 (WP4), Czech Leukemia Study Group for Life (CELL). She is on the advisory board of the patient supportive organization ’Diagnóza leukemie’ and an elected chair of the audit committee of the Czech Hematology Association. She is an author or co-author of more than 70 peer-reviewed articles, four scholarly books and eight peer-reviewed textbooks or textbook chapters.

    Prof. Daniela Žáčková discloses: Advisory board and speakers bureau fees from Angelini and Novartis. Consultancy fees from Angelini and Novartis. Travel support from Angelini, Bristol Myers Squibb, Novartis and Pfizer.
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    Selecting the optimal treatment for patients with chronic myeloid leukaemia after two prior lines of therapy

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    Learning Objectives

    After watching this activity, participants should be better able to:

    • Discuss the treatment for patients with CML after two prior lines of therapy in clinical practice
    • Recall the latest clinical trial data for new and emerging treatments for patients with CML
    • Evaluate the possible impact of new and emerging treatments on the management of patients with CML after two prior lines of therapy
    Overview

    In this activity, two chronic myeloid leukaemia (CML) experts, Prof. Simona Soverini and Dr Daniela Žáčková, discuss the selection of optimal treatment for patients with CML after two prior lines of therapy. They consider the mechanisms of action and the latest clinical efficacy data of current and emerging therapies, and how these may impact the management of CML after two prior lines of therapy. The discussion is guided by pre-canvassed questions provided by the haematology oncology clinical community.

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    Topics covered in this activity

    Haematological Malignancies / Haematology / Leukaemia
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    This Activity Is Funded By:

    An independent medical education grant from Novartis. This activity is provided by touchIME.

    Unapproved products or unapproved uses of approved products may be discussed by the faculty; these situations may reflect the approval status in one or more jurisdictions. The presenting faculty have been advised by touchIME to ensure that they disclose any such references made to unlabelled or unapproved use. No endorsement by touchIME of any unapproved products or unapproved uses is either made or implied by mention of these products or uses in touchIME activities. touchIME accepts no responsibility for errors or omissions.

    This content is intended only for healthcare professionals.

    Launch date: 3 November 2022.

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    touchIN CONVERSATION
    Selecting the optimal treatment for patients with chronic myeloid leukaemia after two prior lines of therapy

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    This Activity Is Funded By:

    An independent medical education grant from Novartis. This activity is provided by touchIME.

    Unapproved products or unapproved uses of approved products may be discussed by the faculty; these situations may reflect the approval status in one or more jurisdictions. The presenting faculty have been advised by touchIME to ensure that they disclose any such references made to unlabelled or unapproved use. No endorsement by touchIME of any unapproved products or unapproved uses is either made or implied by mention of these products or uses in touchIME activities. touchIME accepts no responsibility for errors or omissions.

    This content is intended only for healthcare professionals.

    Launch date: 3 November 2022.

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