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3d illustration of human body liver
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Allan A Lima Pereira, Gabriel Lenz, Tiago Biachi de Castria

Despite being considered a rare type of malignancy, constituting only 3% of all gastrointestinal cancers, the incidence of biliary tract cancers (BTCs) has been increasing worldwide in recent years, with about 20,000 new cases annually only in the USA.1–3 These cancers arise from the biliary epithelium of the small ducts in the periphery of the liver […]

Alexey Danilov, ASH 2019: Advancing the Role of BTK Inhibitors in B-Cell Malignancies

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Published Online: Dec 18th 2019

At the 61st ASH Annual Meeting & Exposition, Alexey Danilov discusses his presentation: Advancing the Role of BTK Inhibitors in B-Cell Malignancies: Expert Guidance for Clinical Management.

Questions

1. What have been the most important recent advances in the use of BTK inhibitors in B-cell malignancies? (0:05)

2. What factors should be considered when selecting the most appropriate BTK inhibitors for an individual? (1:27)

3. What are the major obstacles to the first-line use of BTK inhibitors in B-cell malignancies and how can these be overcome? (3:12)

4. What are likely to be the future challenges and research directions in the use of BTK inhibitors for B-cell malignancies? (4:50)

 

Alexey Danilov is a consult for Janssen, Pharmacyclics, AstraZeneca, Beigene, Verastem, Genentech, Gilead, Nurix, Curis and TG Therapeutics. He has received research funding from AstraZeneca, Gilead, Genentech, Verastem, BMS and Bayer.

Filmed at the 61st ASH Annual Meeting & Exposition 2019, Orlando, FL, USA.

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