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Inflammation of the breast in women. Female breasts with signs of the disease. A low-poly construction of interconnected lines and points. Blue background.
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Mohammad Ammad Ud Din, Hania Liaqat, Ayesha Tayyab

The incidence rate of breast cancer (BC) is the highest in Pakistan among all Asian countries.1 In 2018 alone, 2.1 million cases were diagnosed, although the exact number is likely much higher due to poor reporting in rural areas and the lack of a formal national cancer registry.1,2 Over the last decade, multiple non-governmental organizations and large […]

Bernd Jilma, ASH 2022: The pathophysiology and unmet treatment needs in cold agglutinin disease

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Published Online: Jan 11th 2023

Cold agglutinin disease (CAD) is a rare, autoimmune, clonal B cell disorder. In this touchONCOLOGY interview, we speak with Dr Bernd Jilma (Medical University of Vienna, Vienna, Austria) to discuss the pathophysiology of CAD and the unmet treatment needs in this disease.

The abstract entitled ‘Trial in Progress: Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 3 Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients with Cold Agglutinin Disease (CASCADE)’ (Abstract #2333)  was presented at ASH Annual Meeting, 10–13, December, 2022.

Question:

Could you tell us a little about cold agglutinin disease (CAD), its pathophysiology and the unmet needs in its treatment? (0:17)

Disclosures: Bernd Jilma is on the advisory board, speaker’s bureau and a consultant for Sanofi as well as having received grant/research support and honoraria from Sanofi. 

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby.

Filmed as a highlight of ASH 2022

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