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3d illustration of human body liver
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Allan A Lima Pereira, Gabriel Lenz, Tiago Biachi de Castria

Despite being considered a rare type of malignancy, constituting only 3% of all gastrointestinal cancers, the incidence of biliary tract cancers (BTCs) has been increasing worldwide in recent years, with about 20,000 new cases annually only in the USA.1–3 These cancers arise from the biliary epithelium of the small ducts in the periphery of the liver […]

James Brugarolas, ASCO 2019 – Advances in sarcomatoid RCC

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Published Online: Jun 11th 2019

At the ASCO 2019 annual meeting, James Brugarolas discusses sarcomatoid renal cell carcinoma, the current challenges and the advances that are defining a new treatment paradigm.

Questions

1. What is sarcomatoid renal cell carcinoma (RCC) and what is its prognosis? (0:04)
2. What are the major treatment challenges in sarcomatoid RCC? (0:54)
3. Why is sarcomatoid RCC particularly responsive to immune checkpoint blockade? (1:40)
4. What is the impact on patient survival? (2:45)
5. What further data are needed for checkpoint inhibitors to become the standard of care in sarcomatoid RCC? (3:11)

Speaker disclosure: James Brugarolas has nothing to disclosure in relation to this video interview.

Filmed at the American Society of Clinical Oncology (ASCO) 2019 Annual Meeting, Chicago, IL, USA.

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