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Can advances in antibody-drug conjugate design translate into meaningful survival benefits across more tumor types and earlier treatment settings, without unacceptable toxicity? Having transformed treatment for HER2-positive breast cancer, ADCs are now taking center stage in Madrid, featuring in one-third of the Presidential Symposium late-breaking abstracts. These studies illustrate a shift from established HER2-directed approaches, toward a broader landscape of targets, payloads and clinical applications. In this article, we examine the key trials to watch and the clinical questions they aim to address.
With the European Society for Medical Oncology (ESMO) Congress 2026 fast approaching, attention is turning to Madrid, where the meeting is held from 23–27th October. Whether you are joining onsite or via the virtual platform, the three Presidential Symposia are the sessions not to miss. This year they carry 12 late-breaking abstracts (LBAs) spanning melanoma, lung, genitourinary, gastrointestinal, gynecological and rare cancers. With close to 300 scientific and educational sessions to choose from, we know the programme can feel overwhelming. So we have put together a quick guide to the headline sessions: when and where they run, who is presenting, and links to explore each one in the programme planner, so you can decide which to prioritize.
The impact on patients diagnosed with tenosynovial giant cell tumour (TGCT) can be profound. It is characterized by high recurrence rates, chronic symptoms, and frequent delays in specialist care. Although it is a benign tumor, diffuse TGCT often requires complex multidisciplinary management similar to that used in sarcoma care. In this interview, Dr Sydney Stern (Head of TGCT Support Programs) discusses the evolving treatment landscape, the promise of targeted therapies, and the role of patient advocacy in improving outcomes for people living with this rare tumour.
We often focus on clinical excellence, but spend less time developing broader skills that could help us better lead with purpose and build more fulfilling, impactful careers. In this episode, part of a mini-series in partnership with LEADderm, Dr Jennifer Soung and Denise Mann explore how clinicians can engage with the media to educate, empower and extend their impact beyond the clinic.
Desmoid tumours are rare, locally aggressive soft-tissue tumours that are challenging to manage, due to lack of approved therapies, and variable presentation. Dr Bernd Kasper (Universitätsmedizin Mannheim, Mannheim, Germany) joins touchONCOLOGY to discuss the phase 3 DeFi study, a global ...
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