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Rat sarcoma virus (RAS) proteins are a family of prototypical oncogenes frequently mutated in human cancers. Mutations in the RAS gene account for 19% of all pathogenic alterations and are the subject of extensive research in molecular and clinical oncology.1 The RAS family consists of three major isoforms, namely the Harvey rat sarcoma virus (HRAS), the neuroblastoma RAS […]

Wadie Bahou, ASH 2018 – Platelets and Platelet-related Biomarkers in Tumor Biology and Metastasis

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Published Online: Dec 10th 2018

Dr Wadie Bahou answers our questions about the role of platelets in tumor biology and metastasis and the significance and usefulness of platelet-related biomarkers in the detection and monitoring of hematologic and oncologic diseases.

Questions:
1. What is the role of platelets in tumor biology and metastasis? (0:10)
2. Which platelet-related biomarkers have proven useful in the detection and monitoring of hematologic and oncologic diseases? (1:44)
3. How can these be quantified? (3:02)
4. What research has demonstrated the clinical significance of these biomarkers? (3:51)
5. What further studies are planned in this area? (4:51)

Speaker’s disclosures: Wadie Bahou has nothing to declare in relation to this video interview.

Filmed at the 60th American Society of Hematology (ASH) 2018 Annual Meeting, San Diego, CA, US, December 1–4, 2018.

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