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Circulating tumor DNA (ctDNA) has emerged as an innovative and minimally invasive tool in precision oncology. With a short half-life of 30–120 min, ctDNA provides real-time insight into tumor dynamics.1 In early-stage breast cancer, there is growing evidence supporting its potential for minimal residual disease (MRD) detection and recurrence monitoring. In metastatic breast cancer (MBC), ctDNA […]

John Marshall, ASCO GI22: Recent Advances in Upper Gastrointestinal Cancers

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Published Online: Mar 8th 2022

touchONCOLOGY were thrilled to speak to Editorial Board member Professor John Marshall (Medstar Georgetown University Hospital, Washington, DC, USA) to summarise the latest developments and data from the ASCO Gastrointestinal Cancers Symposium 2022.

The phase III CheckMate 577 Study (NCT03044613): https://meetings.asco.org/abstracts-presentations/204867

KEYNOTE-062 (NCT02494583): https://meetings.asco.org/abstracts-presentations/204515

JCOG NExT study (UMIN000014795): https://meetings.asco.org/abstracts-presentations/204882

Questions:

  1. Could you give us a brief overview of neoantigen based therapies and their clinical development to date in upper gastrointestinal cancers? 00:16-02:41
  2. Which other recent advances in upper gastrointestinal cancers would you like to highlight? 02:47-3:57

Speaker Disclosure: John Marshall has no conflicts of interest to declare in relation to this video.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Sophie Nickelson.

Filmed in coverage of the ASCO Gastrointestinal Cancers Symposium 2022.

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