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It is with great pleasure that we present the latest edition of touchREVIEWS in Oncology & Haematology. This issue highlights the remarkable progress and innovation shaping the fields of oncology and haematology, featuring articles that delve into both emerging therapies and the evolving understanding of complex malignancies. We open with an editorial by Mohammad Ammad […]

Gloria Huang, ASCO 2019 – NRG Oncology/Gynecologic Oncology Group 210 trial

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Published Online: Jun 10th 2019

Gloria Huang discusses results from the NRG Oncology/Gynecologic Oncology Group 210 trial at the ASCO 2019 annual meeting. The trial investigates sex hormone, insulin and insulin-like growth factor signaling in the recurrence of high stage endometrial cancer.

Questions

1. What is known about the role of sex hormone, insulin and insulin-like growth factor (IGF) axis signalling pathways in the development of endometrial cancer? (0:03)
2. What evidence exists for the use of metformin as a treatment for endometrial cancer? (0:44)
3. What other methods of targeting sex hormone, insulin and IGF axis signalling pathways appear promising? (1:27)
4. What were the findings of your study investigating these pathways in the recurrence of high-stage endometrial cancer? (2:41)
5. What are the clinical implications of these findings? (3:33)

Speaker disclosure: Gloria Huang has nothing to disclose in relation to this video interview.

Filmed at the American Society of Clinical Oncology (ASCO) 2019 Annual Meeting, Chicago, IL, USA.

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