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Highlights Immunotherapy, especially combinatory immunotherapy, has shown promise with prolonged survival for patients with advanced mesothelioma in the first-line setting (see the sections on ‘Systemic treatment and immunotherapy debut’ and ‘Randomized immunotherapy trials of mesothelioma’). Histology-based therapy is important to consider, with non-epithelioid subtypes responding better to immunotherapy than to chemotherapy (see the section on […]

Paul Richardson, EHA 2018 – Combination therapy in multiple myeloma: the OPTIMISMM trial

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Published Online: Jun 20th 2018

Paul Richardson from the Dana-Farber Cancer Institute and Harvard Medical School provides an overview of the key findings of the OPTIMISMM trial and discusses the need for new treatment strategies in multiple myeloma.

1. Why is there a need for new combinations of therapies in relapsed/refractory multiple myeloma? (0:09)

2. Could you tell us a little about the study design and what doses were used? (2:51)

3. What were the efficacy and safety findings of the combination? (4:22)

4. What other combined therapies are being considered for future studies? (5:10)

Speaker disclosures: Paul Richardson has nothing to disclose in relation to this video interview.

Filmed at the 23rd Annual Congress of the European Association of Hematology (EHA), Stockholm, Sweden, June 14–17 2018

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