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Allan A Lima Pereira, Gabriel Lenz, Tiago Biachi de Castria

Despite being considered a rare type of malignancy, constituting only 3% of all gastrointestinal cancers, the incidence of biliary tract cancers (BTCs) has been increasing worldwide in recent years, with about 20,000 new cases annually only in the USA.1–3 These cancers arise from the biliary epithelium of the small ducts in the periphery of the liver […]

Oluwatoyosi Muse, ASH 2019: Thrombosis Incidence and the UPR in Pancreatic Cancer

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Published Online: Dec 18th 2019

At the 61st ASH Annual Meeting & Exposition, Oluwatoyosi Muse, Harvard Medical School, discusses her study findings on thrombosis incidence and the unfolded protein response in pancreatic cancer?

Questions

1. What is known about thrombosis incidence and the unfolded protein response (UPR) in pancreatic cancer? (0:05)

2. Could you tell us a little about the design and objectives of your recent study investigating the role of UPR signaling in the prothrombotic transformation of pancreatic cancer? (1:09)

3. What were the findings of this study? (2:23)

4. What do these findings tell us about pancreatic cancer associated thrombosis? (3:14)

5. What were the limitations of this study and what future studies are planned? (3:36)

 

Oluwatoyosi Muse has no conflicts of interest to declare in relation to this video.

Filmed at the 61st ASH Annual Meeting & Exposition 2019, Orlando, FL, USA.

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