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Endocrine therapy (ET) has changed the natural history of hormone receptor-positive (HR+) breast cancer (BC) and is the cornerstone of the treatment of HR+ BC. There are several ETs approved for the treatment of BC, including selective oestrogen receptor modulators (SERMs; tamoxifen), aromatase inhibitors (AIs; anastrazole, letrozole and exemestane) and selective oestrogen receptor degraders (SERDs; fulvestrant […]

Oluwatoyosi Muse, ASH 2019: Thrombosis Incidence and the UPR in Pancreatic Cancer

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Published Online: Dec 18th 2019

At the 61st ASH Annual Meeting & Exposition, Oluwatoyosi Muse, Harvard Medical School, discusses her study findings on thrombosis incidence and the unfolded protein response in pancreatic cancer?

Questions

1. What is known about thrombosis incidence and the unfolded protein response (UPR) in pancreatic cancer? (0:05)

2. Could you tell us a little about the design and objectives of your recent study investigating the role of UPR signaling in the prothrombotic transformation of pancreatic cancer? (1:09)

3. What were the findings of this study? (2:23)

4. What do these findings tell us about pancreatic cancer associated thrombosis? (3:14)

5. What were the limitations of this study and what future studies are planned? (3:36)

 

Oluwatoyosi Muse has no conflicts of interest to declare in relation to this video.

Filmed at the 61st ASH Annual Meeting & Exposition 2019, Orlando, FL, USA.

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