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Emerging Cell Therapy Approaches in Relapsed/Refractory Acute Myeloid Leukaemia in Older Adults

Manan Shah, Nicholas Yuhasz, Hannah Choe

Acute myeloid leukaemia (AML) is a heterogeneous haematologic cancer associated with clonal expansion of myeloid blasts in the bloodstream, bone marrow and other tissues. AML is associated with blasts expressing various complex molecular and cytogenetic alterations, which play an important role in disease prognostication. The median age of AML diagnosis is 67 years with nearly […]

touchREVIEWS in Oncology & Haematology. 2025;21(1):1–6:Online ahead of journal publication

Haematology

The 1st Online Master class in Transplantation and Hematology (MATH) by IACH

Published Online: Mar 20th 2020

The International Academy for Clinical Hematology (IACH) welcomes you to attend the 1st Online Master class in Transplantation and Hematology (MATH)

Saturday, June 6, 2020

For more information, click here.

ZUMA-23 study of axicabtagene ciloleucel as first-line therapy in large B-cell lymphoma: Jason Westin, EHA 2023

ZUMA-23 (NCT05605899) is an on-going phase 3 study investigating axicabtagene ciloleucel (axi-cel) CAR T cell therapy as a first-line therapy in patients with high-risk large B-cell lymphoma. touchONCOLOGY caught up with Dr Jason Westin (The University of Texas MD Anderson Cancer Center, Houston, TX, USA) to discuss what previous clinical trials have taught us about […]

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Axicabtagene ciloleucel for the treatment of large B-cell lymphoma: Jason Westin, EHA 2023

Axicabtagene ciloleucel (axi-cel) is an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy approved to treat patients with relapsed/refractory large B-cell lymphoma. We caught up with Dr Jason Westin (The University of Texas MD Anderson Cancer Center, Houston, ...

Developed by Touch

Bernd Jilma, ASH 2022: Pegcetacoplan in patients with cold agglutinin disease, the CASCADE phase III trial

The CASCADE trial aims to assess the efficacy and safety of pegcetacoplan in patients with cold agglutinin disease (CAD). In this touchONCOLOGY interview, we speak with Dr Bernd Jilma (Medical University of Vienna, Vienna, Austria) to discuss the CASCADE trial ...

Developed by Touch

Bernd Jilma, ASH 2022: The pathophysiology and unmet treatment needs in cold agglutinin disease

Cold agglutinin disease (CAD) is a rare, autoimmune, clonal B cell disorder. In this touchONCOLOGY interview, we speak with Dr Bernd Jilma (Medical University of Vienna, Vienna, Austria) to discuss the pathophysiology of CAD and the unmet treatment needs in ...

Developed by Touch

Srdan Verstovsek, ASH 2022: Momelotinib long-term safety in myelofibrosis disease - Analysis of SIMPLIFY-1, SIMPLIFY-2, and MOMENTUM trials

Momelotinib, an oral JAK1/JAK2/ACVR1 inhibitor, was evaluated in 3 randomised controlled trials - SIMPLIFY-1, SIMPLIFY-2, and MOMENTUM, in patients with high- and intermediate-risk myelofibrosis. In this touchONCOLOGY interview, we speak with Prof. Srdan Verstovsek (MD Anderson Cancer Center, Houston, ...

Developed by Touch

Saskia Middeldorp, ASH 2022: The efficacy of low-molecular-weight heparin in women with recurrent miscarriage and inherited thrombophilia - the ALIFE 2 trial

Studies have linked recurrent miscarriage with inherited thrombophilia. The ALIFE 2 trial aimed to assess the efficacy of low-molecular-weight heparin (LMWH) therapy in women with recurrent miscarriage and inherited thrombophilia. In this touchONCOLOGY interview, we speak with Professor Saskia Middeldorp (Radboud ...

Developed by Touch

Spero R Cataland, Rare Disease Day 2022: Acquired thrombotic thrombocytopenic purpura - Risks, complications and the impact on daily life

Dr Spero R Cataland (The Ohio State University, Wexner Medical Centre, Columbus, OH, USA) joins us for Rare Disease Day to discuss the importance of rapid diagnosis of acquired thrombotic thrombocytopenic purpura (aTTP), a rare blood disorder in which blood ...

Steven Pipe, ASH 2020 – First Results from the HOPE-B Gene Therapy Trial

We had the pleasure to talk to Steven Pipe (University of Michigan, Ann Arbor, MI, USA) to discuss the use of gene therapy for the treatment of haemophilia B. The abstract 'First Data from the Phase 3 HOPE-B Gene Therapy Trial: ...

Efstathios Kastritis, EHA 2020: CYBORD in Amyloidosis and The ANDROMEDA Study

touchONCOLOGY joins Dr Efstathios Kastritis (Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece) at EHA25 Virtual to discuss the ANDROMEDA study (NCT03201965), and the efficacy and safety of daratumumab in combination with CYBORD ...

George Goshua, EHA 2020: Endotheliopathy is Essential in COVID-19 Associated Coagulopathy

Dr George Goshua (Yale University School of Medicine, New Haven, CT, USA) shares with us his insights into the role of endotheliopathy in the development of coagulopathy in patients with COVID-19. Questions: 1. How common is coagulopathy in COVID-19 infection and ...

The 3rd Annual Meeting of the International Academy: Focus on Leukemia

The 3rd Annual Meeting of the International Academy for Clinical Hematology (IACH): Focus on Leukemia October 1-3, 2020 Nice, France. Published Online: 24 February 2020...

TPO agents beyond ITP: aplastic anemia, inherited thrombocytopenia and chemotherapy induced thrombocytopenia

Speaker Prof. James Bussel Learning objectives - Understand that thrombopoietic agents (TPO) impacts the stem cell and thus can have trilineage effects - Recognize that TPO agents are an important way to increase the platelet count in patients with inherited ...

IACH 2019: Welcome

International Academy for Clinical Hematology IACH Prof. Mohamad Mohty The 2nd Annual Meeting of the IACH September 19-21, 2019 | Paris, France Published online: 27 February 2020...

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Emerging Cell Therapy Approaches in Relapsed/Refractory Acute Myeloid Leukaemia in Older Adults

Conference Coverage

Learning Activities

Journals

Emerging Cell Therapy Approaches in Relapsed/Refractory Acute Myeloid Leukaemia in Older Adults

The 1st Online Master class in Transplantation and Hematology (MATH) by IACH

ZUMA-23 study of axicabtagene ciloleucel as first-line therapy in large B-cell lymphoma: Jason Westin, EHA 2023

Axicabtagene ciloleucel for the treatment of large B-cell lymphoma: Jason Westin, EHA 2023

Bernd Jilma, ASH 2022: Pegcetacoplan in patients with cold agglutinin disease, the CASCADE phase III trial

Bernd Jilma, ASH 2022: The pathophysiology and unmet treatment needs in cold agglutinin disease

Srdan Verstovsek, ASH 2022: Momelotinib long-term safety in myelofibrosis disease - Analysis of SIMPLIFY-1, SIMPLIFY-2, and MOMENTUM trials

Saskia Middeldorp, ASH 2022: The efficacy of low-molecular-weight heparin in women with recurrent miscarriage and inherited thrombophilia - the ALIFE 2 trial

Spero R Cataland, Rare Disease Day 2022: Acquired thrombotic thrombocytopenic purpura - Risks, complications and the impact on daily life

Steven Pipe, ASH 2020 – First Results from the HOPE-B Gene Therapy Trial

Efstathios Kastritis, EHA 2020: CYBORD in Amyloidosis and The ANDROMEDA Study

George Goshua, EHA 2020: Endotheliopathy is Essential in COVID-19 Associated Coagulopathy

The 3rd Annual Meeting of the International Academy: Focus on Leukemia

TPO agents beyond ITP: aplastic anemia, inherited thrombocytopenia and chemotherapy induced thrombocytopenia

IACH 2019: Welcome

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