Trending Topic

3D Rendered Medical Illustration of Male Anatomy - Colon Cancer; Ascending Colon.
17 mins

Trending Topic

Developed by Touch
Mark CompleteCompleted
BookmarkBookmarked

Rat sarcoma virus (RAS) proteins are a family of prototypical oncogenes frequently mutated in human cancers. Mutations in the RAS gene account for 19% of all pathogenic alterations and are the subject of extensive research in molecular and clinical oncology.1 The RAS family consists of three major isoforms, namely the Harvey rat sarcoma virus (HRAS), the neuroblastoma RAS […]

Sabina Chiaretti, ASH 2019: Blinatumomab in Relapsed/Refractory Adult ALL

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Published Online: Dec 18th 2019

At the 61st ASH Annual Meeting & Exposition, Sabina Chiaretti, “Sapienza” University of Rome, discusses her presentation: Role of Blinatumomab in Minimal Residual Disease and Hematologic Relapsed/Refractory Adult Acute Lymphoblastic Leukemia Patients Treated over 5 Years. A Single Center Experience.

Questions

1. What are the limitations of current therapeutic options for patients with relapsed/refractory acute lymphoblastic leukemia (ALL)? (0:05)

2. What is the mechanism of action of blinatumomab? (0:54)

3. What were the major findings of your retrospective study? (1:46)

4. What did the study findings teach us about the safety profile of blinatumomab and how to manage toxicities? (2:58)

5. How are these findings likely to impact on clinical practice? (4:43)

 

Sabina Chiaretti has received consultancy fees from Amgen, Shire, Pfizer and incyte.

Filmed at the 61st ASH Annual Meeting & Exposition 2019, Orlando, FL, USA.

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Close Popup