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Esophageal cancer (EC) is a major global health concern, ranking as the 11th most commonly diagnosed cancer and the seventh leading cause of cancer-related deaths worldwide, with an estimated 494,320 new cases and 441,994 deaths in 2024.1 Esophageal squamous cell carcinoma (ESCC) remains the predominant subtype globally (84% of new cases), while esophageal adenocarcinoma (EAC) […]

Benjamin A Weinberg, ASCO GI22: Pivotal Studies in Pancreatic Cancer

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Published Online: Mar 8th 2022

touchONCOLOGY were thrilled to speak to Professor Benjamin A Weinberg (Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA) to discuss the data from the TRYbeCA-1, KRYSTAL-1 and CISPD3 trials, which were presented at the ASCO Gastrointestinal Cancers Symposium 2022.

Questions

  1. What are the hopes of the new drug delivery mechanism using L-asparaginase to treat advanced pancreatic cancer? 00:15-01:13
  2. Why did the TRYbeCA-1 study fail to meet its primary endpoint? 01:13-02:53
  3. How have KRAS G12C inhibitors impacted clinical practice? 02:53-04:33
  4. What can you conclude from the updated results from the KRYSTAL-1 trial in KRAS G12C+ gastrointestinal cancers Cancers? 04:33-06:13
  5. How do you see the future for drug development in advanced pancreatic cancer? 06:14-08:19

Speaker Disclosure: Benjamin A Weinberg has no conflicts of interest to declare in relation to this video.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Sophie Nickelson.

Filmed in coverage of the ASCO Gastrointestinal Cancers Symposium 2022.

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