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Circulating tumor DNA (ctDNA) has emerged as an innovative and minimally invasive tool in precision oncology. With a short half-life of 30–120 min, ctDNA provides real-time insight into tumor dynamics.1 In early-stage breast cancer, there is growing evidence supporting its potential for minimal residual disease (MRD) detection and recurrence monitoring. In metastatic breast cancer (MBC), ctDNA […]

Raajit Rampal, ASH 2019: New Approaches to the Individualized Management of MPNs

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Published Online: Dec 18th 2019

At the 61st ASH Annual Meeting & Exposition, Raajit Rampal, Memorial Sloan Kettering Cancer Center, discusses his presentation: Approaches to the Individualized Management of MPNs: Best Practices and Guidance to Optimize Care.

Questions

1. Given the variable nature of myeloproliferative neoplasms (MPNs), what is the best way of assessing symptom burden? (0:05)

2. How has increased knowledge of the molecular biology of MPNs affected patient management? (0:42)

3. With an increasingly complex treatment regimen, what factors should be considered when selecting and sequencing therapies? (1:55)

4. What novel therapeutic targets are being investigated for MPNs? (3:19)

5. When and how should response assessment be performed? (4:39)

 

Raajit Rampal has received consultancy fees from Incyte Constellation, Celgene, Blueprint, Stemline, Promedior, Kartos.

Filmed at the 61st ASH Annual Meeting & Exposition 2019, Orlando, FL, USA.

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