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Testicular Choriocarcinoma with Inexplicably High Beta-human Chorionic Gonadotropin and Renal Metastases

Published Online: December 23rd 2020 Oncology & Hematology Review (US). 2020;16(2):Online ahead of journal publication
Authors: Jatin Sarin, Rimpi Bansal, Puneet Kaur, Anureet Kaur, Akshita Sarin
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Abstract
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Abstract:
Overview

Choriocarcinoma of testes is a very rare tumor, occurring either in pure form or as part of mixed germ cell tumor. The primary route of metastases of choriocarcinoma is hematogenous because the tumor is extremely vascular. The germ cell tumors otherwise have a propensity for lymphatic spread. The most common presentation in such patients is due to symptoms arising from the metastases of tumor to sites such as the lungs, liver, gastrointestinal tract, spleen, brain and adrenal glands. We report this case of a young male of primary testicular choriocarcinoma who had renal metastasis, which was discovered during the process of evaluation. This is a rare site of metastases, which can result in spontaneous renal hemorrhage and hematuria. β-HCG level of our patient was extremely high, 886,270 mIU/ml, which indicates a high tumor load in the body and subsequent poor outcome.

Keywords

Testicular choriocarcinoma, β-HCG, renal metastases, seminoma

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**This manuscript has been accepted for publication, but may be subject to minor changes during the production process.**

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Disclosure

Jatin Sarin, Rimpi Bansal, Puneet Kaur, Anureet Kaur and Akshita Sarin have no financial or non-financial relationships or activities to declare in relation to this article.

Compliance With Ethics

Informed consent was received from the patient involved in this case study.

Review Process

Double-blind peer review.

Authorship

The named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship of this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval for the version to be published.

Correspondence

Rimpi Bansal, Chandigarh Cancer and Diagnostic Centre, SCO No. -23, SECTOR – 33-D, Chandigarh- 160020, India.
E: rimpijatinsarin@yahoo.com

Support

No funding was received in the publication of this article.

Open Access

This article is freely accessible at touchONCOLOGY.com © Touch Medical Media 2020.

Received

2020-03-18

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