touchREVIEWS in Oncology & Haematology – Volume 21, Issue 2 – 2025
We are pleased to present the latest edition of touchREVIEWS in Oncology & Haematology, featuring cutting-edge insights across cancer care. This issue explores evolving therapies for advanced hepatocellular carcinoma, the role of gut microbiota in cancer immunotherapy, and new approaches in cervical cancer management. In haematology, we review advances in treating thrombotic thrombocytopenic purpura and spotlight early-onset lung cancer’s unique challenges. Together, these articles highlight innovation, collaboration, and the ongoing pursuit of improved outcomes in oncology and haematology.
We extend our sincere thanks to all contributors, including our authors, Editor-in-Chief, editorial board members and partners, for their valued support in producing this edition.
We hope you find the content insightful and informative.
Foreword
It is with great pleasure that we present the latest edition of touchREVIEWS in Oncology & Haematology. This edition showcases the continued advances and innovation reshaping cancer care, as well as highlighting the continued unmet needs and challenges associated with more difficult-to-treat cancers. Dr Gabriel Valagni et al. open with an overview of frontline therapy […]
Reviews
Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver, comprising approximately 85% of all primary liver cancers.1 Globally, it ranks as the sixth-most common cancer and the third-leading cause of cancer-related mortality, with over 900,000 new cases and 830,000 deaths estimated in 2020.1 The risk factors for HCC vary according to geographical and socioeconomic […]
The intestinal microbiota, composed of approximately 1,000 species and over 100 trillion micro-organisms, plays a vital role in host physiology, including metabolism, barrier function and immune regulation.1 Disruption of this delicate host–microbiota balance – known as dysbiosis – has been implicated in the development of inflammatory bowel disease, metabolic disorders and various cancers. In recent years, the influence […]
Cervical cancer (CC) is the fourth most common cancer among women worldwide, with an estimated 604,000 new cases and 342,000 CC-related deaths in 2020.1# Approximately 90% of CCs are caused by infection with human papillomavirus (HPV).2 Even though the adoption of both primary (HPV vaccine) and secondary (Pap test and HPV DNA test) preventive measures has […]
The first primary microangiopathic haemolytic anaemia was identified as thrombotic thrombocytopenic purpura (TTP) by Dr Moschowitz in 1924. At that time, the classic pentad of clinical features, still used today, included fever, erythrocyte fragmentation, thrombocytopenia, kidney injury and neurologic injury.1 It is now known that this disease is characterized by the deficiency of a disintegrin and metalloproteinase with thrombospondin-1-like […]
Early-onset lung cancer is typically defined as occurring in individuals aged 18–50 years, although there is no universally accepted definition.1–3 This entity, though rare, poses unique diagnostic and therapeutic challenges. This article synthesizes current evidence on the unique features and management challenges of lung cancer in young adults, spanning epidemiology, risk factors, clinical behaviour, histopathology, molecular alterations, […]
Trending Topic
This issue of touchREVIEWS in Oncology & Haematology brings together a diverse collection of articles reflecting the growing complexity of cancer care and the continued evolution of precision medicine across tumour types. From rare malignancies and treatment-related challenges to emerging targeted therapies and novel biological insights, the contributions highlight both recent progress and the significant […]
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