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Endocrine therapy (ET) has changed the natural history of hormone receptor-positive (HR+) breast cancer (BC) and is the cornerstone of the treatment of HR+ BC. There are several ETs approved for the treatment of BC, including selective oestrogen receptor modulators (SERMs; tamoxifen), aromatase inhibitors (AIs; anastrazole, letrozole and exemestane) and selective oestrogen receptor degraders (SERDs; fulvestrant […]

Louis Williams, ASH 2019: Genetic Segmentation and Targeted Therapeutics for Multiple Myeloma

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Published Online: Dec 18th 2019

At the 61st ASH Annual Meeting & Exposition, Louis Williams, NYU Langone Medical Center, provides a snapshot of his recent article with Oncology & Hematology (US) exploring genetic segmentation and targeted therapeutics for multiple myeloma.

Questions

1. How has increased understanding of the molecular biology of multiple myeloma impacted on risk stratification of patients? (0:05)

2. Could you tell us a little about B-cell maturation antigen targeted therapies? (1:02)

3. What other emerging targeted therapies seem promising? (2:34)

4. With so many new therapies available, how can we best incorporate them into the treatment paradigm? (3:56)

5. What other pathways are potential therapeutic targets? (5:28)

 

Louis Williams has no conflicts of interest to declare in relation to this video.

Filmed at the 61st ASH Annual Meeting & Exposition 2019, Orlando, FL, USA.

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