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Allan A Lima Pereira, Gabriel Lenz, Tiago Biachi de Castria

Despite being considered a rare type of malignancy, constituting only 3% of all gastrointestinal cancers, the incidence of biliary tract cancers (BTCs) has been increasing worldwide in recent years, with about 20,000 new cases annually only in the USA.1–3 These cancers arise from the biliary epithelium of the small ducts in the periphery of the liver […]

Annalisa Chiappella, EHA 2018 – TP53 Mutations in DLBCL: the FIL-DLCL04 Study

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Published Online: Jun 20th 2018

Annalisa Chiapella from Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino in Italy talks to touchONCOLOGY about patients with diffuse large B-cell lymphoma (DLBCL) with a TP53 mutation, and the aims and findings of the FIL-DLCL04 study to help tackle this.

1. Could you tell us a little about the FIL-DLCL04 study and its findings? (0:10)

2. What is the approximate percentage of patients with diffuse large B-cell lymphoma (DLBCL) with a TP53 mutation? (1:41)

3. What was the impact of TP53 mutations on the prognosis of these young patients with DLBCL? (3:03)

4. What treatment strategies are in clinical development for patients with DLBCL and a TP53 mutation? (4:01)

Speaker disclosures: Annalisa Chiappella has nothing to disclose in relation to this video interview.

Filmed at the 23rd Annual Congress of the European Association of Hematology (EHA), Stockholm, Sweden, June 14–17 2018.

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