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Circulating tumor DNA (ctDNA) has emerged as an innovative and minimally invasive tool in precision oncology. With a short half-life of 30–120 min, ctDNA provides real-time insight into tumor dynamics.1 In early-stage breast cancer, there is growing evidence supporting its potential for minimal residual disease (MRD) detection and recurrence monitoring. In metastatic breast cancer (MBC), ctDNA […]

Andrea Gallamini, EHA 2019 – Three-year Update of the ECHELON-1 Study

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Published Online: Jun 27th 2019

We are joined by Andrea Gallamini, at EHA 2019 to discuss his presentation on frontline brentuximab vedotin with chemotherapy for stage 3/4 classical Hodgkin lymphoma: 3-year update of the ECHELON-1 study.

Questions
1. Could you tell us a little about the ECHELON-1 study and its findings? (0:05)
2. What have we learned from the 3-year update of this study? (1:31)
3. Which patients are most likely to respond to this approach and in which patients is it contraindicated? (2:15)
4. How is the role of brentuximab vedotin likely to further involve in the treatment of classical Hodgkin lymphoma? (3:29)
5. How can the issue of brentuximab vedotin resistance be overcome? (4:18)

Andrea Gallamini has no conflicts of interest to declare in relation to this video.

Filmed at the European Hematology Association (EHA) 24th congress 2019, Amsterdam, Netherlands.

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