Trending Topic

3d illustration of human body liver
12 mins

Trending Topic

Developed by Touch
Mark CompleteCompleted
BookmarkBookmarked
Allan A Lima Pereira, Gabriel Lenz, Tiago Biachi de Castria

Despite being considered a rare type of malignancy, constituting only 3% of all gastrointestinal cancers, the incidence of biliary tract cancers (BTCs) has been increasing worldwide in recent years, with about 20,000 new cases annually only in the USA.1–3 These cancers arise from the biliary epithelium of the small ducts in the periphery of the liver […]

Nicolas Girard, AACR 2022: CheckMate-816 Investigating Neoadjuvant Nivolumab Plus Chemotherapy for Non-small Cell Lung Cancer

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Published Online: May 11th 2022

It was a pleasure to talk with Prof. Nicolas Girard (Institut Curie; Versailles Saint Quentin University, Paris, France) to discuss the findings from his analysis of event-free survival in the CheckMate-816 trial, investigating neoadjuvant nivolumab plus chemotherapy for resectable (IB-IIIA) non-small cell lung cancer.

The abstract ‘Nivolumab (NIVO) + platinum-doublet chemotherapy (chemo) vs chemo as neoadjuvant treatment for resectable (IB-IIIA) non-small cell lung cancer (NSCLC): Event-free survival (EFS) results from the phase 3 CheckMate 816 trial.’ (Abstract number CT012) was presented at AACR 2022, 8-13 April, 2022.

Questions

  1. What was the rationale for the use of an immunotherapy-based combination treatment in non-small cell lung cancer (NSCLC)? (0:13)
  2. What were the aims and design of the CheckMate-816 study investigating neoadjuvant nivolumab (NIVO) plus chemotherapy (CHEMO) in NSCLC? (1:20)
  3. What was the rationale for your analysis of event-free survival in the CheckMate-816 trial? (2:37)
  4. What were the findings from your analysis? (3:44)
  5. What do these findings mean for clinical practice and what further studies are needed? (5:07)

Disclosures: Nicolas Girard has nothing to disclose in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.

Filmed in coverage of the AACR annual meeting 2022.

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Close Popup