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Inflammation of the breast in women. Female breasts with signs of the disease. A low-poly construction of interconnected lines and points. Blue background.
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Mohammad Ammad Ud Din, Hania Liaqat, Ayesha Tayyab

The incidence rate of breast cancer (BC) is the highest in Pakistan among all Asian countries.1 In 2018 alone, 2.1 million cases were diagnosed, although the exact number is likely much higher due to poor reporting in rural areas and the lack of a formal national cancer registry.1,2 Over the last decade, multiple non-governmental organizations and large […]

Nicolas Girard, AACR 2022: CheckMate-816 Investigating Neoadjuvant Nivolumab Plus Chemotherapy for Non-small Cell Lung Cancer

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Published Online: May 11th 2022

It was a pleasure to talk with Prof. Nicolas Girard (Institut Curie; Versailles Saint Quentin University, Paris, France) to discuss the findings from his analysis of event-free survival in the CheckMate-816 trial, investigating neoadjuvant nivolumab plus chemotherapy for resectable (IB-IIIA) non-small cell lung cancer.

The abstract ‘Nivolumab (NIVO) + platinum-doublet chemotherapy (chemo) vs chemo as neoadjuvant treatment for resectable (IB-IIIA) non-small cell lung cancer (NSCLC): Event-free survival (EFS) results from the phase 3 CheckMate 816 trial.’ (Abstract number CT012) was presented at AACR 2022, 8-13 April, 2022.

Questions

  1. What was the rationale for the use of an immunotherapy-based combination treatment in non-small cell lung cancer (NSCLC)? (0:13)
  2. What were the aims and design of the CheckMate-816 study investigating neoadjuvant nivolumab (NIVO) plus chemotherapy (CHEMO) in NSCLC? (1:20)
  3. What was the rationale for your analysis of event-free survival in the CheckMate-816 trial? (2:37)
  4. What were the findings from your analysis? (3:44)
  5. What do these findings mean for clinical practice and what further studies are needed? (5:07)

Disclosures: Nicolas Girard has nothing to disclose in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.

Filmed in coverage of the AACR annual meeting 2022.

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