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Gabriela Franco Katz, Beatriz Mendes Awni Cidale, Ana Zélia Leal Pereira

This article examines current evidence supporting the use of neoadjuvant immunotherapy in patients with resectable macroscopic stage III melanoma and critically discusses the selection of appropriate adjuvant therapy following surgery. It is written in the context of emerging evidence from recent neoadjuvant trials, both in melanoma and across multiple tumor types, suggesting that pathologic response […]

IBRAHIM EL HOUSSIENY, EHA 2019 – CAR-T cells and manufacturing (Part 1)

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Published Online: Jul 3rd 2019

Ibrahim El Houssieny joins us at the EHA annual meeting in Amsterdam to discuss the most important recent therapeutic advances and manufacturing of CAR-T cells. This is part 1 of his interview, part two can be viewed here.

Questions
1. What have been the most exciting recent developments in CAR-T cell therapy? (0:05)
2. Which patient subgroups are most likely to respond to this therapeutic approach? (1:40)
3. What are the major challenges in the manufacturing of CAR-T cells? (3:28)

Ibrahim El Houssieny has no conflicts of interest to declare in relation to this video.

Filmed at the European Hematology Association (EHA) 24th congress 2019, Amsterdam, Netherlands.

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