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Esophageal cancer (EC) is a major global health concern, ranking as the 11th most commonly diagnosed cancer and the seventh leading cause of cancer-related deaths worldwide, with an estimated 494,320 new cases and 441,994 deaths in 2024.1 Esophageal squamous cell carcinoma (ESCC) remains the predominant subtype globally (84% of new cases), while esophageal adenocarcinoma (EAC) […]

Omid Hamid, ASCO 2021: Nemvaleukin Alfa and the ARTISTRY-2 Trial

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Published Online: Jul 13th 2021

touchONCOLOGY joins Dr Omid Hamid (Chief, Translational Research and Immunotherapy, Director, Melanoma Therapeutics, The Angeles Clinic and Research Institute, Los Angeles, CA, USA) at ASCO 2021 to discuss nemvaleukin alfa and the ARTISTRY-2 trial.

The abstract ‘Selection of the recommended phase 2 dose (RP2D) for subcutaneous nemvaleukin alfa: ARTISTRY-2’ (NCT03861793) (abstract number 2552) was presented at the 2021 ASCO Annual Meeting.

Abstract

Poster

Questions
1. Could you tell us a little about nemvaleukin alfa and its mechanism of action? (0:15-01:32)

2. What are the aims of the ARTISTRY clinical trial program, and what have we learned to date? (01:32-02:49)

3. Which tumour types were included in ARTISTRY-2? (02:49-04:09)

4. What were the efficacy and safety findings of ARTISTRY-2? (04:09-05:15)

5. What will be the next steps in the ARTISTRY clinical trial program? (05:15-07:26)

Disclosures: Consulting/Advisory Boards: Aduro, Akeso, Amgen, Beigene, Bioatla, BMS, Roche Genentech, GSK, Immunocore, Idera, Incyte, Janssen, Merck, Nextcure, Novartis, Pfizer, Sanofi/Regeneron, Seattle, Genetics, Tempus, Zelluna. Speaker Bureau: BMS, Novartis, Pfizer, Sanofi/Regeneron. Contracted Research (For Institution): Arcus, Aduro, Akeso, Amgen, Bioatla, BMS, CytomX, Exelixis, Roche Genentech, GSK, Immunocore, Idera, Incyte, Iovance, Merck, Moderna, Merck-Serono, NextCure, Novartis, Pfizer, Sanofi/Regeneron, Seattle Genetics, Torque, Zelluna.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Helen Fowler.

Filmed in coverage of the 2021 ASCO Annual Meeting.

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