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Circulating tumor DNA (ctDNA) has emerged as an innovative and minimally invasive tool in precision oncology. With a short half-life of 30–120 min, ctDNA provides real-time insight into tumor dynamics.1 In early-stage breast cancer, there is growing evidence supporting its potential for minimal residual disease (MRD) detection and recurrence monitoring. In metastatic breast cancer (MBC), ctDNA […]

Robin Foà MD, EHA 2019 – CAR-T cells in the treatment of haematological malignancies

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Published Online: Jun 26th 2019

At the EHA annual meeting in Amsterdam, Editorial Board member Robin Foà joins us to discuss the latest initiatives surrounding CAR-T cells and their use in the treatment of haematological malignancies.

Questions

1. What are the major challenges to incorporating CAR-T cells into clinical practice? (0:06)
2. Where are CAR-T cells likely to fit into the treatment paradigm for haematological malignancies? (1:46)
3. Why is it important to quantify minimal residual disease in haematological malignancies? (2:57)
4. How have new molecular technologies impacted on the evaluation of minimal residual disease? (4:30)
5. How will this breakthrough impact future clinical practice? (5:48)

Professor Robin Foà has no conflicts of interest in relation to this video.

Filmed at the European Hematology Association (EHA) 24th congress 2019, Amsterdam, Netherlands.

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