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Gabriel Valagni, Nkafu Bechem Ndemazie, Tiago Biachi de Castria

Trifluridine/tipiracil (FTD/TPI) is a novel oral formulation of two drugs with promising results in the treatment of metastatic colorectal cancer (mCRC).1 Trifluridine is a thymidine-based nucleoside analogue that, after intracellular phosphorylation, gets incorporated into DNA, causing DNA dysfunction.2 It was first identified by Callahan et al. in 1996 as an active impurity in the herbicide trifluralin, which […]

Lyudmila A Bazhenova, WCLC 2021: Challenges of Widespread Immunotherapy

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Published Online: Nov 30th 2021

touchONCOLOGY joins Prof Lyudmila A Bazhenova (University of California San Diego, CA) at WCLC 2021 to discuss the challenges faced when expanding patients receiving immunotherapy for the treatment of non-small cell lung cancer.

Questions
1. What has been the impact of immunotherapy in the treatment of non-small cell lung cancer (NSCLC)? (00:12-00:51)
2. What are the current challenges to the widespread use of immunotherapy? (00:51-02:19)
3. What factors affect the decision to prescribe immunotherapy to a patient with NSCLC? (02:19-02:56)
4. What are the challenges to expanding who gets immunotherapy and how can these be overcome? (02:56-04:09)
5. What further research is needed? (04:09-05:09)

Disclosures: Lyudmila Bazhenova has been an advisory board member for Merck, Daichi Sankyo, Turning Point, Janssen, Novartis, Neuvogen, BMS and Boehringer Ingelheim. She also discloses stock for Epic Sciences.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Sophie Nickelson.

Filmed in coverage of the 2021 WCLC Annual Meeting.

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